Company Profile

Tissue Regeneration Systems Inc (AKA: TRS)
Profile last edited on: 8/20/19      CAGE: 47SF9      UEI:

Business Identifier: Biomaterials to stimulate bone and soft tissue growth
Year Founded
2005
First Award
2009
Latest Award
2012
Program Status
Inactive
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Location Information

46701 Commerce Center Drive
Plymouth, MI 48170
   (425) 576-4032
   info@tissuesys.com
   www.tissuesys.com
Location: Multiple
Congr. District: 11
County: Wayne

Public Profile

Tissue Regeneration Systems (TRS) is a medical device company commercializing a breakthrough skeletal reconstruction and bone regeneration technology platform licensed from the Universities of Michigan and Wisconsin. Validated by numerous in vitro and in vivo studies, including several large animal trials with very promising long term resultss, the firms has completed required bench and animal testing and received 510K clearance from the FDA for technology platform and first commercial product. This platform has two novel and proprietary components. One: to utilize proprietary and scalable 3D printing methods to fabricate advanced skeletal reconstruction implants that have unique attributes. Bioresorbable over time, fully replacing themselves with natural bone and leaving no residual implanted device. Although their micro-architecture is porous to facilitate bone integration, this porosity is fully engineered so that the implant can bear significant load and support function, allowing for use in a broad range of complex procedures as an alternative to harvested bone. Using input from patient CT scans, their geometry can be custom constructed and, if necessary, adapted in the operating room to exactly replicate and replace missing bone anatomy. The firm's Affinity™ coating technology allows TRS to integrate implants with an osteoconductive, mineral coating that enhances bone regeneration and proliferation into and throughout the porous implant. Affinity™ has a plate-like nanostructure that resembles living bone and serves as an excellent substrate for adhesion of autologous cells and growth factors, such as BMP, which can be added intra-operatively and released in a controlled manner to accelerate new bone formati

Extent of SBIR involvement

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Synopsis: Awardee Business Condition

Employee Range
15-19
Revenue Range
1.5M-2M
VC funded?
Yes
Public/Private
Privately Held
Stock Info
----
IP Holdings
N/A

Awards Distribution by Agency

Most Recent SBIR Projects

Year Phase Agency Total Amount
2012 2 NIH $971,066
Project Title: Designed Bioactive Scaffolds for Mandibular Reconstruction
2011 1 NIH $203,350
Project Title: Coated Scaffolds For Intra-Operative Protein Incorporation And Controlled Release

Key People / Management

  Jim Fitzsimmons -- President and Chief Executive Officer

  James Adox -- Chairman of the Board

  Hank Brown -- Board Member

  Stephen E Feinberg -- Founder

  Scott J Hollister -- Founder And Board Member

  Leenaporn Jongpaiboonkit

  Frank La Marca -- Founder and Board Member

  Jongpaiboonkit Leenaporn

  William L Murphy -- Founder

  Rachel Schek