SphereVis LLC is developing a simple, generic, optical super-resolution method of imaging biological and photonic structures that can overcome the spatial resolution limitations of microscopes. The technology SphereVis is developing can provide two- to three-fold enhanced spatial resolution capabilities.The imaging resolution of a standard optical microscope is limited to ~250 nm. Improved optical imaging resolution would enable better intra-cellular imaging for medical diagnoses and therapies. The firm is is developing novel microscope cover slides composed of arrays of high-index microspheres embedded in elastomers, such as Polydimethylsiloxane (PDMS).
