xD Bio Inc., a privately held, Montana-based company collaboratinf with at the Encyclopedia of DNA Elements (ENCODE) Data Coordinating Center (DCC) at Stanford University to demonstrate the ability to run advanced computational analyses developed by the ENCODE DCC directly through a web interface on xD Bio's web based platform, Truwl.com. Truwl is xD Bio's flagship product designed to enable Users to find, understand, use, and share computational methods for DNA sequencing data on a publicly available web-based platform. Generating large sequencing datasets is increasingly common in the biomedical space requiring thos einvolved to have access to system thatcan support their making sense of the data. With XD Bio Truwl systems designed to be user-friendly and to provide a centralized site for researchers to explore and collaborate on methods, the intetis to remove some of the barriers in the data analysis process. The proposed web interface and connected cloud compute infrastructure under development is intended to allow researchers to run analyses directly from Truwl without having to configure their own compute environments. Focusing on the thoroughly vetted, high impact methods developed by the ENCODE DCC will provide maximum value to the genomics research community.