Voxeleron LLC is organzied around development state-of-the-art software in the field of computer vision and machine learning. The specialty of principals is in the development of ophthalmic image analysis software for optical coherence tomography (OCT) imagery.Focus is on significantly expanding and enhancing Voxelerons OrionTM image analysis software for studying optical coherence tomography (OCT) images of the human retina. The effort is to enable this platform to provide the first device-independent and commercially available software that can perform analyses, static or longitudinal, on the thicknesses of the layers of the retina directly associated with photo-receptor and neuronal degeneration. Such capability could facilitate the development of new and robust clinical biomarkers for the diagnosis and monitoring of diseases like age-related macular degeneration (AMD), diabetic retinopathy (DR), glaucoma, Alzheimers, Parkinsons, multiple sclerosis (MS), and amyotrophic lateral sclerosis (ALS). By validating segmentation algorithms across devices and time this work could accelerate the pace of discovery and understanding of both ocular and neurodegenerative diseases. Dr. Pearse Keane, MD, FRCOphth, is an NIHR clinician scientist at the Institute of Ophthalmology, UCL, and an honorary consultant ophthalmologist at Moorfields Eye Hospital. Specialising in age-related macular degeneration and diabetic retinopathy, Dr. Keane is an expert in ophthalmic OCT and is a leading collaborator in the effort to bring advanced analysis techniques to clinical practice. Professor Pablo Villoslada is an adjunct professor at UCSF and the Director of the Visual Pathway Lab at IDIBAPS in Barcelona. His focus is on the development of new therapies, biomarkers and diagnostic methods for MS and other autoimmune and brain diseases. He has particular interest in OCT imaging of the anterior visual pathway, and how the retina can be used as a marker of neurodegeneration in MS and other diseases.
