Underdog Pharmaceuticals Inc is structured around addressing the development of easy-to-use (by the patient) of drugs that target common age-related problems. Such an issue would be a common underlying causative factor e.g. arterial plaque build up. An initial primary focus is tackling the removal of arterial plaque that typically forms and accmulates within cells in the arterial walls. The company develops simple and direct interventions targeting toxic forms of cholesterol, using rationally designed molecules, to provide the first true disease-modifying treatments for age-related diseases such as atherosclerosis, hypercholesterolemia, heart failure, and macular degeneration.