Transposagen Biopharmaceuticals, Inc., a biotechnology company providing animal models, cell lines, stem cells, and research tools and technologies to improve drug discovery and development research offers site-specific nucleases targeting various genes in the human genome; genetically modified rat models, including knockout, knock-in, humanized, conditional, transgenic, and inducible rats; and rat tissues, custom rat models, in-bred and out-bred transgenic services, various disease models, and cell line and stem cell services. The firm offers its animal models for various human diseases, including human cardiovascular diseases, diabetes, and arthritis, as well as various autoimmune, neurological, and behavioral disorders. Transposgen's genetically modified animals using multiple genetic manipulation technologies - to include proprietary mobile DNA piggyBac technology and spermatogonial stem cells - serves pharmaceutical and biotechnology companies, academic laboratories and health institutes worldwide.