Acquired by MediChem in June 2000, Thermogen had been organized around creating stable enzymes for industrial applications. The firm supplied of stable enzyme biocatalysts and biotransformation processes for pharmaceutical, agrochemical, specialty chemical and pharmaceutical intermediate markets. Custom developed enzyme discovery and implementation tools included proprietary enzyme libraries and gene banks, biocatalyst engineering and evolution systems (such as ThermoGenetic stabilization and ThermoFusion systems), and methods for rapid enzyme/mutant screening and process optimization. Biocatalysis and enzymologyThermoGen has reduced the time required to develop a complex biocatalyst from two years to six months with new improvements imminent.
