Tango Biosciences has developed a method for the discovery of recombinant affinity reagents through phage-display, which creates "sandwich" assay that increases both sensitivity and specificity. The solution, MegaSTAR, identifies two-site capable binders (i.e., pairs) as part of the phage-display affinity selection process. By relying upon two independent affinity reagents that recognize distinct epitopes, the sandwich assay increases both sensitivity and specificity. The company also produces fresh biomarkers and proteins using bacterial and mammalian cell culture and in vitro transcription and translation.
