Company Profile

Sixone Solutions LLC
Profile last edited on: 12/30/21      CAGE: 6BH19      UEI:

Business Identifier: Treating breast cancer and other cancers using drugs that minimize toxic side effects
Year Founded
2010
First Award
2013
Latest Award
2013
Program Status
Inactive
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Location Information

12635 East Mountview Boulevard Suite 145
Aurora, CO 80045
   (303) 638-3521
   N/A
   www.sixonesolutions.com
Location: Single
Congr. District: 06
County: Adams

Public Profile

SixOne Solutions LLC is a biopharmaceutical company developing novel products for the treatment and diagnosis of breast cancer. SixOne Solutions’s long-term goal is to introduce drugs to the market that will not only inhibit the growth of tumors in breast cancer but also treat other cancers. Principals of the firm have been studying a particular group of molecules, called Eya2 and Six1, for about a decade. That complex of molecules contributes to an overgrowth of cells and migration of cells to different parts of the body. That’s what leads to the spread of cancer and growth in tumors. If researchers figure out a way to disrupt the complex, they could possibly stop the spread of cancer and the growth of tumors. For now, they’ve decided to focus on inhibitors that can disrupt the complex in patients with triple-negative breast cancer. There are currently no targeted therapies for that type of cancer, so doctors have to prescribe rounds of either chemotherapy or radiation therapy, or both, to those patients. Chemotherapy and radiation are physically taxing because they have so many side effects, including hair loss, vomiting, weight loss, and even secondary tumors and heart problems. By zoning in on therapies for triple-negative breast cancer patients, the need for chemotherapy could lessen - reducing the side effects of those treat

Extent of SBIR involvement

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Synopsis: Awardee Business Condition

Employee Range
1-4
Revenue Range
Less than .5M
VC funded?
No
Public/Private
Privately Held
Stock Info
----
IP Holdings
N/A

Awards Distribution by Agency

Most Recent SBIR Projects

Year Phase Agency Total Amount
2013 1 NIH $292,886
Project Title: The Anti-Tumorigenic and Anti-Metastatic Potential of Eya Phosphatase Inhibitors

Key People / Management

  Virginia "Ginny" Orndorff -- CEO

  Heide L Ford -- Scientific Founder

  Aaron Patrick -- Senior Scientist

  Rui Zhao -- Scientic Founder