
SignaBlok Inc Profile last edited on: 12/3/19
CAGE: 5Z7P9
UEI: JM5UN38YM1H7
Business Identifier: Peptide-based technology to block disease-causing signals from T cells Is this YOUR Company?
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Location Information
Location: Single
Congr. District: 02
County: Worcester
Congr. District: 02
County: Worcester
Public Profile
SignaBlok, Inc. is a biopharmaceutical company developing a new class of therapies â innovative modulatory peptides that can be rationally designed for nearly any cell surface receptor and have broad potential to treat and prevent a wide range of serious diseases with unmet clinical needs. Designated SCHOOL - signaling chain homo-oligomerization - the system is a method of silencing intracellular communication, This novel model of cell signaling - SCHOOL - uncovers the mechanisms of signaling by membrane receptors, a biological process that plays an important role in health and disease; a discovery that potentially opens new avenues for drug development with applications in many serious diseases. SignaBlok is also developing a nanotechnology that enables targeted delivery of SCHOOL peptides and other therapies and/or imaging agents, aiming to improve efficacy, reduce dose, and allow image-guided therapy
Extent of SBIR involvement
Synopsis: Awardee Business Condition
Employee Range
1-4Revenue Range
Less than .5MVC funded?
NoPublic/Private
Privately HeldStock Info
----IP Holdings
5-9Awards Distribution by Agency
Most Recent SBIR Projects
Year | Phase | Agency | Total Amount | |
---|---|---|---|---|
2023 | 1 | NIH | $272,741 | |
Project Title: New mechanism-based TREM-1 therapy for acute respiratory distress syndrome | ||||
2023 | 1 | NIH | $278,127 | |
Project Title: First-in-class TREM-1 inhibitors for neovascular retinal diseases | ||||
2020 | 1 | NIH | $249,601 | |
Project Title: TREM-1 Inhibitor for the Treatment of Scleroderma | ||||
2020 | 2 | NIH | $2,224,562 | |
Project Title: First-in-class TREM-1 inhibitors in combination therapy for pancreatic cancer | ||||
2020 | 1 | DHA | $220,006 | |
Project Title: First-in-class TREM-1 Radioprotector to Prevent the Effects of Acute Radiation Syndrome |
Key People / Management
Alexander B Sigalov -- President and Founder