Company Profile

Sentien Biotechnologies Inc
Profile last edited on: 5/28/2020      CAGE: 59MH0      UEI: NDAYRDKCMBJ7

Business Identifier: Novel therapeutics for acute indications characterized by systemic inflammation, including COVID-19.
Year Founded
2008
First Award
2010
Latest Award
2017
Program Status
Inactive
Popularity Index
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Location Information

99 Hayden Avenue Building E Suite 140
Lexington, MA 02421
   (781) 361-9031
   info@sentienbiotech.com
   www.sentienbiotech.com
Location: Single
Congr. District: 05
County: Middlesex

Public Profile

Sentien Biotechnologies, Inc. is a clinical stage company developing novel approaches to cell therapy. The firm's lead product combines mesenchymal stromal cells (MSCs) within an approved blood-filtration device, allowing for controlled, sustained delivery of MSC secreted factors. Product being tested to treat systemic inflammatory diseases where MSCs can condition blood continuously during an acute illness.. Sentien’s mission is to harness power of cell therapy with innovative drug delivery systems to treat a wide range of acute inflammatory diseases. The firm's lead product is designed to allow for controlled, sustained delivery of mesenchymal stem cell (MSC) secreted factors - an approach that immobilizes the MSCs in an extracorporeal device, allowing for doses of therapeutic secreted factors that are unattainable by direct injection. in the fall 2016, Boehringer Ingelheim named Sentien its first LabCentral Golden Ticket winner. The Golden Ticket program enables high-level sponsors to underwrite the cost of a lab bench for a scientist to reside in the innovative, shared laboratory space for one year.

Extent of SBIR involvement

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Synopsis: Awardee Business Condition

Employee Range
15-19
Revenue Range
1.5M-2M
VC funded?
Yes
Public/Private
Privately Held
Stock Info
----
IP Holdings
1-4

Awards Distribution by Agency

Most Recent SBIR Projects

Year Phase Agency Total Amount
2017 2 NIH $1,812,586
Project Title: Stem Cell Bioreactor for Cardiac Care
2016 2 NIH $4,324,245
Project Title: A Mesenchymal Stem Cell Bioreactor for the Active Treatment of Acute Renal Failur
2013 2 NIH $499,306
Project Title: Cellular Device For The Treatment Of Acute Liver Failure
2012 1 Army $99,974
Project Title: Blood Purification for Organ Failure
2010 1 NSF $150,000
Project Title: Assembly and Storage of Cell-Derived Drug Delivery Devices

Key People / Management

  Brian T Miller -- Co-Founder and CEO, President

  Rita Barcia -- Director of Research and Development

  Chris Gemmiti -- Vice President of Operations

  Jack Milwid -- Co founder

  Biju Parekkadan -- Scientiifc Co-Founder

  Biju Parekkadan

  Arno W Tilles