Picoyune is a chemical sensing company whose patented technology(ies) are designed around replacing a laboratory's worth of equipment with handheld monitors anyone can use. Anchored in more than a decade of research at the University of California, Berkeley and the Lawrence Berkeley National Lab., the first target for this approach was mercury - a potent neurotoxin increasingly subject to regulation for removal and remediation. Based on the firm's capabilities and market-fit, Picoyune has received numerous awards at startup accelerators and business plan competitions. From the earky start-up of the firm, the effort has been to engage with potential customers to determine their needs - effectively the business strategy is to merge technical excellence with keen business development to provide better sensors that clients wil buy.