Company Profile

NABsys Inc (AKA: Nab Sys Inc)
Profile last edited on: 3/3/2023      CAGE: 4LFM6      UEI: JJF3CLN56NN7

Business Identifier: Development of solid-state, single-molecule positional sequencing technology
Year Founded
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Location Information

60 Clifford Street
Providence, RI 02903
   (401) 276-9100
Location: Single
Congr. District: 01
County: Providence

Public Profile

Having been the first company to receive a "$1000 Genome" award from the National Human Genome Research Institute of the National Institutes of Health for an electronic approach to sequencing DNA, Nabsys uses proprietary electronic nano-channel detectors to analyze long DNA molecules at high velocity. Electronic detection enables Nabsys to achieve significantly higher resolution than can be obtained using optical mapping methods. Nabsys HD-Mapping™ solid-state electronic nano-channel detectors build whole genome maps with sub-diffraction-limit resolution that are truly high definition. These maps offer compelling advantages for the analysis of structural variation, the assembly of genomes, and as a method for confirming putative variants called using other technologies. HD-Mapping works by adding sequence-specific tags to long DNA molecules. These molecules pass through the nano-detectors at high velocity using a combination of electrophoretic and hydrodynamic control. The detectors report the locations of the sequence-specific tags on the molecules. The information is then analyzed by Nabsys analytical software. Key application areas that are enabled by Nabsys include: • De Novo Assembly • Structural Variant Discovery • Variant Verification • Microbiome Analysis • Metagenome Characterization • Hybrid Assembly Nabsys provides the complete solution for electronic genome mapping. The Nabsys HD-Mapping platform includes: • HD-Mapping instrument • Electronic nano-channel detector chips • Complete run reagent cartridge • Sample prep kit • Comprehensive control and data analysis software. Nabsys HD Mapping provides routine, accurate, cost-effective analysis of genomic structural information. The HD-Mapping platform employs fully electronic detection of tagged single DNA molecules to provide significantly higher sensitivity, accuracy, scalability and speed of detection in comparison to existing mapping technologies. Single-molecule reads, hundreds of kilobases in length, have high resolution and low error rates, resulting in high information content per read.

Extent of SBIR involvement

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Synopsis: Awardee Business Condition

Employee Range
Revenue Range
VC funded?
Privately Held
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IP Holdings

Awards Distribution by Agency

Most Recent SBIR Projects

Year Phase Agency Total Amount
2008 2 NIH $497,734
Project Title: Hybridization-Assisted Nanopore Sequencing

Key People / Management

  Barrett Bready -- Founder and CEO

  Jennifer Davis -- Associate Director

  Mike Kaiser -- Vice President of Software & Informatics

  Darren Lee -- Vice President Business Development

  Steve Numberg -- Executive VP of Product Development

  John S Oliver -- Chief Technology Officer

  Brian Paras -- Vice President of Commercial Development