Company Profile

LayerBio Inc
Profile last edited on: 2/5/20      CAGE: 701U8      UEI: K3QGXETK35W8

Business Identifier: Sustained release drug delivery for ophthalmology, wound care and other therapeutic areas
Year Founded
2013
First Award
2015
Latest Award
2019
Program Status
Active
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Location Information

196 Boston Avenue Suite 1000
Medford, MA 02155
   (617) 905-2544
   info@layerbio.com
   www.layerbio.com
Location: Single
Congr. District: 05
County: Middlesex

Public Profile

Anchored in technology developed at MIT in the laboratory of its Co-Founders, Dr. Paula Hammond, LayerBio is developing novel drug delivery products for ophthalmology, wound care, tendon repair and other unmet medical needs. LayerBio’s patented platform, LayerForm™, is a conformal, tunable and bioerodible polymer technology that enables coating and release of drugs from various medical devices. The product is compatible with small molecules, nucleic acids and biologic drugs and has been tested on a variety of substrates, including bandages, sutures, ophthalmic lenses and other topical and implantable devices: numerous potential applications for LayerBio’s distinctive technology. A current area of focus by the firm is development of its sustained-release formulation of the glaucoma drug travoprost. Glaucoma is the leading cause of irreversible blindness worldwide - in the US alone, an estimated 2.2 million people suffer from the disease. The typical first-line treatment for glaucoma is a topical eye drops. However, lack of continuous dosing and issues with patient compliance limit the effectiveness of topical eye drops for preventing progression of the disease - making the 24 hour sustained-release formulations an important alternative to eye drops. LayerBio's sustained-release glaucoma formulation is based on its PolyNet™ platform - a novel network polymer-based drug delivery technology invented at LayerBio personnel. Other applications for the patented LayerForm technology would be implant and wound healing applications and drug-coated implants for cataract lens replacement that have currently to be applied as drops after s

Extent of SBIR involvement

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Synopsis: Awardee Business Condition

Employee Range
1-4
Revenue Range
Less than .5M
VC funded?
No
Public/Private
Privately Held
Stock Info
----
IP Holdings
N/A

Awards Distribution by Agency

Most Recent SBIR Projects

Year Phase Agency Total Amount
2019 2 NIH $1,225,363
Project Title: Sustained Release Travoprost Implant for Treatment of Glaucoma
2017 1 NIH $324,930
Project Title: Platform Delivery Technology for Nucleic Acid Therapeutics to Promote Wound Healing
2015 1 NIH $262,610
Project Title: Drug-Eluting Intraocular Lens
2015 1 NSF $179,958
Project Title: Multi-month, Nanoparticle Drug Delivery System for the Treatment of Glaucoma

Key People / Management

  Kenneth J Mandell -- President & CEO

  Paula T Hammond -- Founder & Chair of the Sab

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