Our laboratory is interested in the control of morphogenesis by homeobox genes. The homeobox genes provide the highest level of control during embryonic development. While the molecular genetics of the homeobox genesis now well established, the genes controlled by the homeobox genes is currently unknown. We are currently testing a new theory, proposed by Gerald Edelman, that postulates that the homeobox genes primarily regulate the expression of cell adhesion proteins and their receptors. We are also interested in a new area, termed tissue engineering. Tissue engineering involves creating tissues and organs from single cells. We have developed a computerized technique that permits one to microposition cells within a cell diameter on any substratum