HeartMetrics, Inc. has developed a diagnostic algorithm for quantifying blood flow from a standard computed tomography angiography (CTA) image of the heart. The company's technology, known as Transluminal Attenuation Flow Encoding (TAFE) is based on contrast dispersion fluid dynamics and is aimed at identifying coronary diseases that cause a reduction of blood flow to the heart muscle. The use of this technology to identify vessel specific ischemia greatly facilitates decisions about whether patients should be referred to the catheterization laboratory/operating room for invasive therapy or be managed by medications only. The company's co-founder is a Professor of Mechanical Engineering and Medicine at Johns Hopkins University and is a recognized international expert in computational fluid dynamics and cardiovascular fluid dynamics.