GPB Scientific has offices and laboratories on both UScoasts, and maintains grant-based R&D at leading academic centers. The firm's main operations are in Vista, CA, with a business development office in Cambridge, MA and business office in Richmond, VA. GPB also collaborates in ongoing academic research & development programs, GPB Scientific is a cell-separation company, marketing its technology to life sciences companies and research establishments. The company has accumulated an extensive portfolio of patents and know-how utilizing microchip technology for size-based enrichment and/or for affinity-based cell capture. Although the technology can be customized for the enrichment of cells of interest from a variety of media, the company currently focuses on blood fractionation. Using the company's microfluidic chip technology, close to 100% of white blood cells can be isolated for further analysis while removing red blood cells and platelets to undetectable levels. GPB's technology features fully automated technology, a very gentle process, reduced sample handling and labor costs, offering a superior process for the fractionation of whole blood, with no lysis of blood cells or hemoglobin contamination taking place. Leukocytes, including granulocytes, are able to be quantitatively isolated using this technique. The firm's liquid biopsy platform supports obtaining rare circulating tumor cells at their viable state from the patient's blood. Also offered is a desktop fluidic system for cell separation that pumps blood through a disposable microchip. The company?'s fluidic system processes a tube of whole blood to remove and separate red cells and normal white cells, resulting in a viable population of rare tumor cells.
