Company Profile

GeneTAG Technology Inc
Profile last edited on: 1/22/2020      CAGE: 47UK2      UEI: N78BHV2RJKJ8

Business Identifier: Precise, simple and inexpensive Molecular Detection Systems
Year Founded
2005
First Award
2009
Latest Award
2022
Program Status
Active
Popularity Index
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Location Information

3781 Presidential Parkway Suite 9
Atlanta, GA 30340
   (678) 805-8840
   info@genetagtech.com
   www.genetagtech.com
Location: Single
Congr. District: 04
County: DeKalb

Public Profile

GeneTAG offers seven different DNA Detection Switch (DDS) probe systems specialized for high-fidelity detection (error-checking probes) or for low-cost detection (generic-component probes). Employing two interacting components: a fluorescent labeled probe and a nearly complementary quencher-labeled antiprobe, probes preferentially bind to their intended targets, liberating fluorescence. Specificity is enhanced by providing an excess of antiprobes that intercept any incorrect hybridizations between probes and off-targets, thereby preventing false positives. Error-checking DDS probes: Conventional dual-labeled qPCR probes lack error-checking mechanisms and cannot provide multi-temperature single base discrimination. The firm’s error-checking DDS probes function either as internal probes (iDDS or Flip probes) or primer-probes (ZIPR probes), wherein each target-specific probe is combined with a slightly mismatched, competitive antiprobe. The antiprobe blocks off-target detection over a wide range of annealing temperatures (up to 30°C), and facilitates multiplexing. The internal probes provide reliable single base discrimination and are also useful for validating next generation sequencing results. ZIPR primer-probes are stringent reference probes that enable 1- or 2-color detection of targets of interest, such as gene fusions occurring in cancer. Primer-probes label all amplicons for maximum signaling. The firm’s internal Flip probe system generates linear amplification curves, which are useful for quantitative real-time or endpoint detection. G-Force probes: these are single-molecule G-Force probes employing guanine-mediated fluorescence quenching by forming a hairpin between adjacent C-rich and G-rich sequences. G-Force probes can also serve as reliable reference probes to provide positive amplicon detection in cases where a second probe is distinguishing a specific mutation, and together, the mutant frequency can be assessed.

Extent of SBIR involvement

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Synopsis: Awardee Business Condition

Employee Range
1-4
Revenue Range
Less than .5M
VC funded?
No
Public/Private
Privately Held
Stock Info
----
IP Holdings
5-9

Awards Distribution by Agency

Most Recent SBIR Projects

Key People / Management

  David A Shafer -- President

  Peixu Hu -- Chief Financial Officer

  James L Murray -- Senior Research Director

Company News

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