With cell purification a critical need in development and production of cutting edge diagnostics and therapeutics, Ferrologix is structured around a unique magnetic-based instrument & disposable cartridge that can transport, filter, and organize single cells for precision analysis or therapeutic manufacture. Anchored in a new technique - designated Digital Magnetic Sorting (aka Ratcheting Cytometry) - Ferrologix is developing a suite of tools to assist, accelerate, and scale the development of precision medicine research, next gen diagnostics, and cellular therapies. That core capability involves employing an array of inexpensive magnetic micropillars patterned onto a plastic substrate to form a single use cartridge. When subjected to a rotating magnetic field cells which have been labeled with a magnetic antibody can be precisely manipulated in a massively parallelized format. Various chip designs can execute a variety of functions such as rapid cell purification, quantitative separation based on surface expression, and cell co-localization with transduction/transfection reagents. Advantages: Quick: 10X faster than current magnetic purification platforms; Quantitative: Separate specific cell subtypes; Closed: Aseptic operation to meet GMP standards and Continuous: Compatible with large volumes and cell quantities
