In January 2019, it was announced that Pulse Therapeutics had merged with ICHOR Vascular to created the newly-formed entity Euphrates Vascular with the merged entity positioned in the treatment of vascular occlusions with an initial focus on the Limb Ischemia market. Subsequent efforts are transition to the technologies beyond the peripheral vascular occlusions that had been the Pulse Therapeutic focus into Ischemic Stroke, Coronary, Wound Care, Dialysis, Interventional Oncology, and Orthopedic applications. Incorporated in 2008 and currently SBIR active in NIH, Pulse Therapeutics, Inc., had been focused on magnetically-enhanced diffusion (MED) system for the treatment of stroke, heart, and other diseases. The firm had developed a mechanical thrombolysis technology that accelerates the delivery of clot-busting drugs to a clogged artery. The Magnetically Enhanced Diffusion (MED) System consists of intravenously administered nanoscale iron particles and a patient-side workstation, whose rotating magnet induces the particles to spin within the bloodstream. is used to harness magnet-based technology to dissolve blood clots faster than current modalities. The company also provides MED MicroBeads that are designed to convey physician-selected agents faster to the blood clot; intravenously administered after thrombolysis therapy is initiated; and mechanical adjunct to standard of care IV thrombolysis. This activity creates flow towards the clot in otherwise stagnant vessels, bringing medications to the clot site 40 times faster than normal. The company had filed an early feasibility investigational device exemption (IDE) with the FDA to enable clinical trials to evaluate the device for strhas developed a mechanical thrombolysis technology that accelerates the delivery of clot-busting drugs to a clogged artery. The Magnetically Enhanced Diffusion (MED) System consists of intravenously administered nanoscale iron particles and a patient-side workstation, whose rotating magnet induces the particles to spin within the bloodstream.
