In September 2004, Epoch Biosciences merged with CA based Nanogen, also an SBIR involved firm. Formerly called Epoch Pharmaceuticals (OTC EPPH ), Epoch Biosciences moved to NASDAQ (EBIO). Epoch Pharmaceuticals Inc. is a biomedical company utilizing nucleoside and nucleotide chemistry to develop molecular tools for genetic analysis. Utilizing unique and proprietary technology in the rational design, synthesis and chemical modification of oligonucleotides, the Company has positioned itself to provide products and techniques for high throughput genetic sequence analysis that are in increasing demand in the rapidly expanding field of genetic pharmacology. Previously, Epoch's therapeutic research and development program had focused on the modification of gene expression by altering cellular genomic DNA using oligonucleotide targeting technology combined with chemical reactivity. Epoch's technology is based on its expertise in designing and synthesizing oligonucleotides bearing modifications that selectively bind to and interact with the target genes.