With ties to the University of Arizona, bioVidria Inc uses silica colloidal crystals as a platform technology for a suite of products for fast biological analysis, with microarray substrates as the first product line. bioVidria, Inc. has licensed new technology from Purdue University that allowed bioVidria to move forward to commercializing UHPLC columns for high resolution separations of protein drugs. RPLC columns enable resolution of isoforms from disulfide scrambling. HILIC columns enable resolution of glycosylation variants, including unglycosylated proteins. BioVidrias technology uses particle sizes as small as sub-0.2um for extraordinary gains in resolution and speed. The use of such tiny particles is enabled by the Purdue groups discovery that these media are dominated by a phenomenon called slip flow, which greatly enhances flow rates in RPLC,