Company Profile

Biocrystal LTD
Profile last edited on: 5/20/2019      CAGE: 1SEB8      UEI:

Business Identifier: Nanocrystal technologies
Year Founded
1996
First Award
2001
Latest Award
2003
Program Status
Inactive (Acquired)
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Location Information

575 McCorkle Boulevard
Westerville, OH 43082
   (614) 818-1170
   jbergen@biocrystal.com
   www.biocrystal.com
Location: Single
Congr. District: 04
County: Delaware

Public Profile

BioCrystal, Ltd. has brought together an interdisciplinary science group into a business structure committed to the development of novel products and procedures for applications in the life sciences and clinical medicine. BioCrystal is focused to product commercialization in three areas: semiconductor-based, nanocrystalline fluorescent markers for cell and intracellular detection and analysis; therapeutic compounds and procedures for the diagnosis and treatment of cancer; and the very innovative OptiCell ®, a product that represents a significant step forward in the evolution of cell and tissue culture technology .Fluorescent Nanocrystals: One of the fundamental tools used in the identification of biological molecules is immunofluorescence, a technique that combines sensitive fluorescent indicators (dyes) with antibodies or proteins that target specific biomolecules in complex mixtures. BioPixels™ , a new series of fluorescent tags, improve this process. BioPixels have narrow emission spectra and resist photobleaching.They are stable in aqueous solutions, and are produced in a series of colors of the visible spectrum – all excitable by the same wavelength of light, and all with narrow, non-overlapping emission spectra. These nanometer-sized crystals are functionalized to allow direct coupling to biological molecules such as proteins, antibodies, lectins and nucleotides. BioCrystal's advanced functionalized coating technology improves fluorescence intensity and biostability. The Treatment of Cancer: Current anticancer therapies basically target the destruction of tumorcells. They marginally address the associated tumor systemic pathology. BioCrystal has discovered the means for controlling tumor biology through a systemic pathology that can be applied in cancer therapy to avoid tumor recurrence and metastasis. The company has demonstrated experimentally that its immune corrective therapy products can significantly reduce the recurrence and spread of cancer. Cell Culture Research Tool - OptiCell ® Since the completion of the Human Genome Project, researchers have focused on the biological behavior and function of a cell population in relation to its genetic profile. Advances in technology have yielded fascinating insights into the ways that cells work. Nonetheless, the fundamental tools for in vitro cell culture have changed little the past 50 years. For the multitude of operations involved in cell culture, a number of different devices and tools are employed, many steps are required, and there is a premium on good laboratory practice to minimize contamination. OptiCell addresses all of these issues. OptiCell improves the efficiency of cell management, reduces the cost of labor in cell and tissue culture practices, creates the means to automate cell culture practices, and will expand the practical use of a disposable cell culture device for diagnostic applications in clinical medicine.

Extent of SBIR involvement

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Synopsis: Awardee Business Condition

Employee Range
10-14
Revenue Range
1M-1.5M
VC funded?
No
Public/Private
Privately Held
Stock Info
----
IP Holdings
25-49

Awards Distribution by Agency

Most Recent SBIR Projects

Year Phase Agency Total Amount
2003 2 Army $799,032
Project Title: Synthesis and Functionalization of Quantum Dots for Bio Agent Detection

Key People / Management

  Jeffrey R Bergen -- President and CEO

  Emilio Barbera-Guillem

  Imad Naasani

Company News

There are no news available.