Aztek Bio LLC (AKA: KL50 Therapeutics LLC~Aztek~Aztek Bio Inc ) Profile last edited on: 11/19/2023
CAGE: 92PE8
UEI: EWKMDMMY8119
Business Identifier: Exploiting DNA repair defects to kill gliomas; plus GeoVaxs Ebola vaccine Is this YOUR Company?
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Location Information
36 Church Lane
Westport, CT 06880
Westport, CT 06880
(203) 272-8658 |
N/A |
N/A |
Location: Single
Congr. District: 04
County: Fairfield
Congr. District: 04
County: Fairfield
Public Profile
Originally dba as KL50 Therapeutics LLC, the firm was renamed Aztek in November 2021, then (a few months later) was announced as doing business as Aztek Bio Inc - jst soon after (in April 2022) was adjusted to Aztek Bio LLC. Yale School of Medicine scientists -- to include Azrec co-founders - revealed in the magazine Science compounds that target drug-resistant gliomas. Most glioma tumors lack the methyl transferase MGMT and initially respond to the DNA methylation agent temozolomide. Frequently, the cells acquire resistance through loss of the mismatch repair (MMR) pathway. Authorsof the article indicated having created agents that cause a dynamic DNA lesion via a two-step chemical process. The first lesion can be reversed by MGMT in healthy cells, but transforms into a more toxic secondary lesion in MGMT-deficient tumor cells, resulting in MMR-independent cell death.
Extent of SBIR involvement
Synopsis: Awardee Business Condition
Employee Range
1-4Revenue Range
Less than .5MVC funded?
NoPublic/Private
Privately HeldStock Info
----IP Holdings
N/AAwards Distribution by Agency
Most Recent SBIR Projects
Key People / Management
Ranjit S Bindra
Seth Herzon
Kingson Lin -- Co-Founder
Seth Herzon
Kingson Lin -- Co-Founder
Company News
There are no news available.