Company Profile

Applied Integrin Sciences Inc
Profile last edited on: 12/11/13      CAGE: 6B5A6      UEI:

Business Identifier: Protein drug therapies for cancer treatments based on integrin receptor modulation
Year Founded
2009
First Award
2012
Latest Award
2013
Program Status
Inactive
Popularity Index
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Location Information

2629 Townsgate Road Sute 235
Westlake Village, CA 91361
   (310) 457-0982
   info@integrins.com
   www.integrins.com
Location: Single
Congr. District: 26
County: Ventura

Public Profile

Applied Integrin Sciences Inc discovers, develops, and commercializes protein drug therapies for cancer treatments that reduce solid tumor growth and progression and improve patient survival and quality of life. The company's founder-Scientists discovered a proprietary drug discovery platform for producing novel protein therapeutics modulating specific Integrin receptors known to be involved in cancer growth, progression, and metastasis. These recombinant proteins affect primary tumors, tumor vasculature, and metastatic Foci involved in Cancer, as in the Metastatic Breast Cancer cell shown in the image above. The novel mechanism of action of Vicrostatin, the company's first candidate, and ADMol, one of the twenty-three proprietary ADAM-derived Disintegrin drug candidates, produces equally substantial reduced tumor progression in six aggessive metastatic tumors in vivo: Triple Negative Breast Cancer, Primary Prostate Cancer, Prostate Cancer Bone Metastasis, Ovarian Cancer, Melanoma, and Glioblastoma.

Extent of SBIR involvement

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Synopsis: Awardee Business Condition

Employee Range
5-9
Revenue Range
.5M-1M
VC funded?
No
Public/Private
Privately Held
Stock Info
----
IP Holdings
N/A

Awards Distribution by Agency

Most Recent SBIR Projects

Year Phase Agency Total Amount
2013 1 NIH $299,937
Project Title: A Novel Brachytherapy Agent for Gbm
2013 1 NIH $458,691
Project Title: Integrin Targeted Therapy for the Treatment of Ovarian Cancer

Key People / Management

  Douglas C Lane -- Chairman, President and CEO

  Thomas C Boone -- CSO

  Frank Calzone

  Thomas C Chen -- Co-Founder

  Francis S Markland -- Co-Founder

  Radu Minea -- Co-Founder

  Stephen Swenson -- Co-Founder