Coming out of work at Univerity of Buffalo, Angiograft., LLC is stuctured around providing solutions for regenerative medicine using innovative cell-free approaches. By making artificial tissue replacements available off-the-shelf capable of developing biological function, the firm's technology platform provides alternative treatment options for vascular and non-vascular applications. The Angiograft mission is to provide life-saving vascular tissue replacement options for patients suffering from cardiovascular diseases. Angiograft A-TEVs (acellular tissue engineered vessels) are usable as arterial and venous replacement grafts,size and site matchable to the patients' need, available off-the-shelf. With Angiograft's cellular technology, A-TEVs are programmed to attract the patients' own cells, healing within the body to form a biological functional blood vessel.Angiograft makes artificial blood vessels for treatment of cardiovascular disease. The fiirm's products are composed of collagenous biomaterials, which are functionalized sequentially with anti-clotting and self-cellularizing proteins. These enable them to attract the patients' own cells once implanted, making them biologically functional. At the end of the healing process, the fortified biomaterial is remodeled leaving behind a functional vascular graft made of the patients' own tissue.
