Early detection of abnormal physiologic parameters and signs of pathology are paramount to the successful implementation of countermeasures that can mitigate the probability of an adverse outcome. Advanced Diagnostic Technologies was working on a Spectroscopic Biosensor able non-invasively to measure target blood analytes with a multivariate approach Depolarization Raman, Absorption, and Scattering coefficients. By remove the requirements for maintaining biologic samples for monitoring a person's health, the system would enable real-time health monitoring. Small in size, easy to use, low in power, be portable. system could provide continuous -- or near continuous -- target analyte monitoring. Target analyte data could be stored and tranmitted as data. Biomedical sensing can be sued to measure specific hormone levels associated with excessive stress, insomnia and psychiatric disorders; measure blood analytes associated with malnutrition ; Noninvasive monitoring. Point-Of-Care device for: Doctorâs office, Home Health Care Agencies, Hospital laboratories, ICU monitoring, Telemedicine client