SBIR-STTR Award

Video Analysis Techniques for Computer-Aided Quality Control for Colonoscopy
Award last edited on: 9/10/2018

Sponsored Program
STTR
Awarding Agency
NSF
Total Award Amount
$765,617
Award Phase
2
Solicitation Topic Code
BT
Principal Investigator
Wallapak Tavanapong

Company Information

EndoMetric LLC

3124 Greenwood Road
Ames, IA 50014
   (515) 292-8444
   N/A
   N/A

Research Institution

----------

Phase I

Contract Number: ----------
Start Date: ----    Completed: ----
Phase I year
2007
Phase I Amount
$199,882
This Small Business Technology Transfer Phase I project will develop algorithms for a quality control system for colonoscopy (a procedure where the mucosa of the large bowel is inspected via a flexible tube with a camera on it) that has contributed to a marked decline in the number of colorectal cancer related deaths. However, recent data suggest that there is a significant miss-rate for the detection of even large polyps and cancers. Anticipated results of this research are: (1) algorithms for colonoscopy to determine whether the beginning of the large bowel was reached; (2) algorithms for detecting the appearance of the appendiceal orifice as the appendix is located at the beginning of the colon, its detection confirms that the entire colon has been traversed; and (3) software tools to derive quality measurements. The broader impacts of this research are that it will enable automated, objective quality control for colonoscopy in large-scale, day-to-day medical settings, which is currently not feasible. This has the potential to benefit the health of millions of people each year. If successful it will initiate new research and development in quaity control for other endoscopic procedures such as bronchoscopy, cystoscopy, and laparoscopy. The project will contribute to medical education, research, and practice by providing videos containing all aspects of typical colonoscopy practice and corresponding quality measurements that can be used for teaching and training of new endoscopists and recertification of previously certified endoscopists.

Phase II

Contract Number: ----------
Start Date: ----    Completed: ----
Phase II year
2010
Phase II Amount
$565,735
This Small Business Technology Transfer (STTR) Phase II project will develop an assistive software tool for endoscopists to have real-time feedback of objective quality for colon and potential polyp region examinations. The technology is aimed to reduce polyp miss rates during colonoscopy. Colonoscopy has contributed to a marked decline in colorectal cancer related deaths. However, recent data suggest that there is a significant miss rate for the detection of even large polyps and cancers. Studies suggest that polyp detection rate may be related to the duration of the withdrawal phase of the procedure and cancer miss rate is related to the identity of the endoscopist performing the procedure. This tool, which will provide video stream analysis and feedback during live colonoscopy, is made up of novel middleware software to ensure high performance execution of video analysis on an affordable workstation, and are generic, reconfigurable with new task allocation that support time-constraint video analysis. Objective metrics for real-time feedback are derived from real time analysis that will address complexities arising from blurry frames, stool, camera movement patterns, and regions of appendiceal orifice and polyps. Technical insights learned from development of this tool for colonoscopy may be applicable to new research on quality control using videos generated in other areas of medicine, such as bronchoscopy, cystoscopy, arthroscopy and laparoscopy.The broader/commercial impact of this project, if successfully implemented in large-scale day-to-day medical settings, will be higher quality of care for patients undergoing colonoscopy procedures with real time objective quality assessment, which is currently not feasible. Over 14 million colonoscopies are performed annually in the US. This assistive tool will stimulate high quality inspection, while documentation is done. That will mean that endoscopists will be able to spend more time on performing the colonoscopy and less time on documentation. Hospital/clinic administrators will be able to run endoscopic facilities more efficiently. Insurance companies may benefit from better documentation and lower costs since fewer patients will require extensive cancer treatment as the frequency of missed polyps and early cancers declines. This assistive tool is also expected to contribute to medical education, research, and practice by providing automated feedback during teaching and training of novice endoscopists or continuing education for experienced endoscopists.