SBIR-STTR Award

This Small Business Technology Transfer Research (STTR) Phase I project proposes to develop a novel microchip based enzyme-linked immunosorbent assay on compact disk (CD-ELISA) for rapid detection of biological molecules. The commercial application of this project will be for detection of food-borne pathogens and toxins. The proposed system is expected to have the advantages of low cost, simple operation, parallel detection, fast response, and ease of automation

The Small Business Technology Transfer (STTR) Phase II project will develop a low-cost and mass-producible lab-on-a-chip platform for molecular and biological analyses. The platform is a microfluidic CD for Enzyme-Linked Immunosorbent Assays (ELISA) that reduces cost, accelerates results, and improves reliability of analyses for food borne contaminants, cancer diagnoses and environmental contamination.The CD-ELISA technology platform merges two scientific areas - polymer microfabrication and biotechnology - and can substantially reduce manufacturing costs, improve device performance, and enable the production of low-cost and high-efficiency devices. Moreover, as such a device would be more affordable it will enable point-of-use results for a broader spectrum of molecular and biological testing.