SBIR-STTR Award

Engineering Geobacter for Enhanced Electricity Production
Award last edited on: 3/25/2024

Sponsored Program
STTR
Awarding Agency
NSF
Total Award Amount
$599,665
Award Phase
2
Solicitation Topic Code
BT
Principal Investigator
Radhakrishnan Mahadevan

Company Information

Genomatica Inc

4757 Nexus Center Drive
San Diego, CA 92121
   (858) 824-1771
   info@genomatica.com
   www.genomatica.com

Research Institution

0548633

Phase I

Contract Number: 2006
Start Date: University of Massac    Completed: 7/1/2004
Phase I year
2004
Phase I Amount
$100,000
This Small Business Technology Transfer Phase I project proposes to improve the bioelectrical energy generation capacity of the micro-organism Geobacter sulfurreducens through a novel metabolic engineering approach based on an integrated computational and experimental strategy. The commercial application of this project will be in the area of biomass processing, for conversion of waste biomass to value added products (i.e. electricity).

Phase II

Contract Number: 0420048
Start Date: 6/30/2005    Completed: 10/1/2006
Phase II year
2006
(last award dollars: 1711372072)
Phase II Amount
$499,665

This Small Business Technology Transfer (STTR) Phase II project aims to develop commercially viable bacterial strains (Geobacter sulfurreducens) for use as biocatalysts in microbial fuel cells. The research genetically manipulates these bacteria to enable the utilization of alternative substrates and increase current generation through the expression of an energy consuming futile cycle. The rates will be increased and alternative cheaper substrates utilized during this project. The broader impact of this research will result in development of novel microbial fuel cells that can convert renewable resources such as biomass and agricultural wastes to electrical energy in an efficient fashion with varied commercial applications. Additionally, innovative the metabolic engineering strategy that is developed could be applied to other industrially relevant microorganisms. In addition, there are significant societal and educational components of this program. One example would be a microbial fuel cell that harnesses electricity from organic waste can be valuable in electrifying remote rural communities in developing countries by decentralizing power generation while protecting the environment.