The objective of this contract is to develop a tool that allows researchers to identify preventions for AD/ADRD through access to and analysis of the vast array of BSR literature. Cognition Causal Association Record Extractor (CognitionCARE) is an AI-based web application that presents AD/ADRD-specific, BSR-related information in a manner that is easy to consume and act upon. CognitionCARE extracts, aggregates, and visually maps the variables and causal relationships described in AD/ADRD focused BSR papers. CognitionCARE will group ontologically related concepts into categories, producing a topically organized overview of AD/ADRD-focused BSR research with user options for in-depth exploration of latent connections between variables. The contractors novel computational semantic approach to biomedical content analysis overcomes current limitations in extracting actionable, high-quality information from large volumes of scientific text, assisting researchers in developing broadly effective interventions for AD/ADRD.
