Chronic Condition-related Fatigue (CCrF) is a distressing sense of physical, emotional and/or cognitive tiredness that negatively impacts the quality of life (reduced workability, poor anti-cancer treatment adherence) and healthcare expenditure (e.g., over $9,322 annually) of those affected. CCrF is a persistent problem across chronic conditions such as cancer, multiple sclerosis, rheumatoid arthritis, and diabetes, which also affects their caregivers. An estimated 5 million people in the United Stated (US) are living with fatigue associated with chronic conditions. Moreover, Latinos are disproportionally affected by fatigue or its contributing factors (e.g., pain and stress) in many of those conditions. Studies suggest the potential of trans-diagnostics interventions (energy preservation, psycho- social education, cognitive behavioral therapy, etc.) for coping with CCrF. However, despite the substantial burden of fatigue, there are no digital health solutions in the market that address the fatigue support needs by applying such trans-diagnostics interventions. Furthermore, often studies of digital health solutions underrepresent minorities, potentially producing health disparities, such as lower adoption by US Latinos. The Adhera® Fatigue Digital Program (AFDP) builds on the principles of transdiagnostics interventions for providing fatigue self-management empowerment to people across different conditions with advanced artificial intelligence-based personalization techniques. The AFDP is part of the Adhera Health's evidence-based Precision Digital CompanionTM platform, which is already being used in dozens of hospitals for various conditions. The objectives of this Phase I project are: Aim 1) Assess the acceptability of the Adhera® Fatigue Digital Program by the US Latino population. Milestone: the AFDP accepted by Latino populations, measured with uMARS (average of 4 out of 5 stars) and SUS (average usability score of more than 75). Aim 2) Design the implementation strategy for AFDP in the urban Latino community. Milestone: Completed implementation strategy and accepted by 3 healthcare providers for initial pilots. The key aspiration for Phase I, combined with further clinical validation in Phase II, is to obtain scientific validation that will set the foundation for the future commercialization of Adhera® Fatigue in a Software-as-a-Service model that will target the healthcare providers and payors that cover the underserved population of US Latinos living with CCrF, which represents a substantial and growing part of healthcare costs in the US.
Public Health Relevance Statement: One of the most prevalent symptoms affecting cancer, multiple sclerosis, rheumatoid arthritis, diabetes patients, and caregivers is chronic condition-related fatigue. This debilitating symptom leaves more than 5M people in the USA underserved, contributing especially to the burden of the Latino community. In this project, we are adapting the Adhera Health's digital health program for fatigue self-management to the US Latino population with the goal of reducing health inequality that is perpetuated with today's lacking digital health alternatives.
Project Terms: Adoption; Affect; Anxiety; Arthritis; arthritic; Rheumatoid Arthritis; Atrophic Arthritis; rheumatic arthritis; Artificial Intelligence; AI system; Computer Reasoning; Machine Intelligence; Malignant Neoplasms; Cancers; Malignant Tumor; malignancy; neoplasm/cancer; Child; 0-11 years old; Child Youth; Children (0-21); kids; youngster; Cognitive Therapy; Cognition Therapy; Cognitive Psychotherapy; cognitive behavior intervention; cognitive behavior modification; cognitive behavior therapy; cognitive behavioral intervention; cognitive behavioral modification; cognitive behavioral therapy; cognitive behavioral treatment; Communities; Diabetes Mellitus; diabetes; Insulin-Dependent Diabetes Mellitus; Brittle Diabetes Mellitus; IDDM; Juvenile-Onset Diabetes Mellitus; Ketosis-Prone Diabetes Mellitus; Sudden-Onset Diabetes Mellitus; T1 DM; T1 diabetes; T1D; T1DM; Type 1 Diabetes Mellitus; Type 1 diabetes; Type I Diabetes Mellitus; insulin dependent diabetes; insulin dependent type 1; juvenile diabetes; juvenile diabetes mellitus; ketosis prone diabetes; type I diabetes; type one diabetes; Disease; Disorder; Education; Educational aspects; Elements; Ethnic Population; Ethnic Group; Ethnic People; Ethnic individual; Ethnicity People; Ethnicity Population; ethnic subgroup; ethnicity group; Health Expenditures; health care expenditure; healthcare expenditure; Fatigue; Lack of Energy; Feedback; Foundations; Future; Goals; Health; Health Personnel; Health Care Providers; Healthcare Providers; Healthcare worker; health care personnel; health care worker; health provider; health workforce; healthcare personnel; medical personnel; treatment provider; Hospitals; Marketing; Mental Health; Mental Hygiene; Psychological Health; Methods; Minority Groups; Minority People; Minority Population; Minority individual; Multiple Sclerosis; Disseminated Sclerosis; insular sclerosis; Persons; Nurses; nurse; Pain; Painful; Parents; parent; Patients; Physicians; Quality of life; QOL; Quantitative Evaluations; Research; Somatotropin; Growth Hormone; Pituitary Growth Hormone; somatotropic hormone; Growth Hormone 1; Stress; United States; Work; Measures; Care Givers; Caregivers; Health Costs; Healthcare Costs; Health Care Costs; health care; Healthcare; Latino; diverse populations; heterogeneous population; population diversity; Population Heterogeneity; Research Methods; research and methods; Research Methodology; Self Management; chronic pain; Site; Chronic; Clinical; Phase; Ensure; Distress; insight; Workshop; Educational workshop; Inequality; uptake; bilingual; bilingualism; tool; Diagnostic; aspirate; programs; Dimensions; Techniques; System; physical conditioning; physical health; psychosocial; Participant; empowerment; Emotional; Modeling; Intervention; Intervention Strategies; interventional strategy; reduce risk; reduce risks; reduce that risk; reduce the risk; reduce these risks; reduces risk; reduces the risk; reducing risk; reducing the risk; risk-reducing; Risk Reduction; disparity in health; health disparity; Address; Symptoms; Cognitive; Underrepresented Minority; Underrepresented Ethnic Minority; under-representation of minorities; under-represented minority; underrepresentation of minorities; Validation; validations; minority health; health literacy; cost; digital; under served group; under served individual; under served people; under served population; underserved group; underserved individual; underserved people; Underserved Population; designing; design; biopsychosocial; coping; Population; anti-cancer treatment; anticancer treatment; usability; addictive disorder; addiction; commercialization; evidence base; treatment adherence; health equity; Health Inequity; Inequalities in Health; Inequities in Health; health inequalities; risk minimization; mobile app; mobile device application; mobile application; software as a service; debilitating symptom; disabling symptom; Service model; care delivery model; health care delivery model; healthcare delivery model; Service delivery model; Alternative Health; preservation; strategies for implementation; implementation strategy; social factors; Long COVID-19; Long coronavirus disease; Long coronavirus disease 2019; chronic COVID; chronic COVID-19; chronic novel coronavirus disease 2019; long haul COVID; long haul COVID-19; long haul coronavirus disease; long haul coronavirus disease 2019; long-hauler COVID; long-hauler COVID-19; long-hauler coronavirus disease 2019; long-hauler syndrome; long-term COVID; long-term COVID-19; long-term coronavirus disease; long-term coronavirus disease 2019; longterm COVID; longterm COVID-19; longterm coronavirus disease; longterm coronavirus disease 2019; post COVID syndrome; post COVID-19 syndrome; post acute COVID syndrome; post acute COVID-19; post acute COVID-19 syndrome; post acute SARS-CoV-2; post acute coronavirus disease 2019; post acute coronavirus disease 2019 syndrome; post acute coronavirus disease syndrome; post acute severe acute respiratory syndrome coronavirus 2; post coronavirus disease 2019 syndrome; post coronavirus disease syndrome; post-acute phases of COVID-19; Long COVID; implementation research design; implementation design; digital health; racial population; Racial Group; racial subgroup; health disparity populations; health disparity community; health disparity group; National Institute on Minority Health and Health Disparities; NCMHD; NIMHD; National Center on Minority Health and Health Disparities; National Institute of Minority Health and Health Disparities; Health Disparities Research; Health disparities related research; health disparities science; Latino Population; Latino group; Latino individual; Latino people; Latinos; minority health disparity; Equity
