SBIR-STTR Award

Treating Drivers of Suicide in Primary Care using Jaspr Health
Award last edited on: 2/16/2024

Sponsored Program
SBIR
Awarding Agency
NIH : NIAAA
Total Award Amount
$2,232,676
Award Phase
2
Solicitation Topic Code
273
Principal Investigator
Linda A Dimeff

Company Information

Evidence-Based Practice Institute LLC

3303 South Irving Street
Seattle, WA 98144
   (206) 265-2507
   support@ebpi.org
   www.practiceground.org
Location: Single
Congr. District: 09
County: King

Phase I

Contract Number: 1R44AA029868-01
Start Date: 9/10/2021    Completed: 8/31/2022
Phase I year
2021
Phase I Amount
$397,990
Suicide remains a serious public health problem in the U.S. as rates have risen nearly each year since 2005, from 11.0 per 100,000 to 14.8 per 100,000 in 2018, totaling 48,344 in 2018; 1.4 million U.S. adults made a suicide attempt, and another 12 million thought seriously about killing themselves that same year. Alcohol use disorder (AUD) exponentially increases suicide risk and can also interfere with suicide prevention intervention efforts. Suicide prevention initiatives over the past decade have targeted healthcare systems (HCS) in general and primary care clinics (PCC) in particular because so many who die by suicide access their primary care provider (PCP) in the months and year prior to their death. Though universal suicide screening is now routinely conducted in PCC, many HCS and PCC struggle to provide suicide prevention evidence-based practices (EBP) on par with other behavioral health EBP commonly treated in PCC. Digital technologies can efficiently and reliably help deliver suicide prevention EBP in PCC and increase the confidence and competence of PCP in treating suicide, including AUD that may interfere with these efforts. Jaspr Health ("Jaspr"; R44MH108222) is a suicide prevention platform originally designed for use by acutely suicidal patients in emergency departments (ED) to deliver suicide prevention EBP. Grounded in Jobes' Collaborative Assessment and Management of Suicidality (CAMS), Jaspr guides patients in completing a comprehensive suicide risk assessment and lethal means counseling, builds a crisis stabilization plan, and teaches behavioral skills to reduce imminent distress; videos of people with live experience (PLE) offer wisdom and hope for getting through suicide crises. Information is summarized for the care team to aid in discharge disposition planning. A companion app provides support post-discharge. Results from a randomized controlled trial (RCT; N=31) comparing Jaspr to Care-as-Usual strongly support its feasibility, acceptability, and effectiveness in increasing delivery of EBP, reducing agitation and distress, improving capacity to cope with suicidal thoughts, and improving ED satisfaction. This 34-month fast track seeks to increase the public health impact of Jaspr Health by extending its utility to deliver evidence-based brief interventions that directly target and treat a person's reasons for wanting to die (their "drivers" for suicide) while simultaneously addressing alcohol misuse. The proposal is defined by three project stages which include: (1) a proof-of-concept formative evaluation stage where we will iteratively design, test, and build a prototype (Phase I; Months 1-10); (2) a product design-and-build formative evaluation stage, where we will design, build and test all remaining features and apps (Phase II; Months 11- 22); and (3) a summative evaluation stage involving a pilot test (N=20) and a RCT (N=120) comparing Jaspr to a suicide prevention app and other online wellness resources (Phase II; Months 23-34).

Public Health Relevance Statement:


Project narrative:
PUBLIC HEALTH RELEVANCE With 47,151 suicides in 2019 and 12 million American adults reporting serious suicidal ideation each year, suicide remains the 10th leading cause of death among all ages and the second leading cause of death among those 10-44 years old in the U.S.; alcohol use disorder (AUD) exponentially increases suicide risk and can also interfere with suicide prevention intervention efforts. The Collaborative Assessment and Management for Suicidality (CAMS) is a flexible tool used to assess, manage, and treat suicidal behaviors. Jaspr Health ("Jaspr") is a robust CAMS-informed evidence-based digital technology that aids in assessing and managing acutely suicidal patients, this fast-track proposal seeks to extend its public health impact by developing brief interventions that directly target individuals' drivers of suicide in a primary care context.

Project Terms:
Adoption; Adult; 21+ years old; Adult Human; adulthood; Age; ages; alcohol use disorder; ethanol use disorder; Cause of Death; comorbidity; co-morbid; co-morbidity; Counseling; Cessation of life; Death; Health; Healthcare Systems; Health Care Systems; Health Personnel; Health Care Providers; Healthcare Providers; Healthcare worker; health care personnel; health care worker; health provider; health workforce; healthcare personnel; medical personnel; treatment provider; Mental Health Services; Mental Hygiene Services; Methods; Movement; body movement; Persons; Occupations; Jobs; Professional Positions; Outpatients; Out-patients; Pain; Painful; Patients; Primary Health Care; Primary Care; Primary Healthcare; Public Health; Resources; Research Resources; Running; Suicide; fatal attempt; fatal suicide; intent to die; suicidality; Suicide attempt; non fatal attempt; nonfatal attempt; suicidal attempt; Technology; Testing; Time; United States; Agitation; Psychomotor Agitation; Psychomotor Excitement; Psychomotor Hyperactivity; Psychomotor Restlessness; Restlessness; Administrator; Competence; Healthcare; health care; Research Methodology; Research Methods; Risk Assessment; Treatment Effectiveness; Caring; base; improved; Procedures; Suicide prevention; Suicide precaution; prevent suicidality; prevent suicide; suicidality prevention; suicide intervention; Acute; Phase; Ensure; Evaluation; Distress; Individual; Recovery; satisfaction; Patient Recruitments; participant recruitment; Randomized Controlled Trials; Contracting Opportunities; Contracts; Companions; tool; Suicidal thoughts; suicidal ideation; suicidal thinking; suicide ideation; thoughts about suicide; Feeling suicidal; suicidal; Clinic; Visit; Emergency Department; Emergency room; Accident and Emergency department; suicide risk; suicidal risk; American; experience; Self Efficacy; skills; Participant; Preventative strategy; Preventive strategy; Prevention strategy; Manpower; personnel; Human Resources; Reporting; feeling distress; feeling upset; emotional distress; brief therapy; brief treatment; brief intervention; behavioral health; Effectiveness; Address; Evidence based practice; Preventative intervention; intervention for prevention; prevention intervention; preventional intervention strategy; preventive intervention; Process; Development; developmental; Behavioral; active control; suicidal behavior; suicide behavior; digital; design; designing; alcohol misuse; ethanol misuse; unhealthy alcohol use; coping; clinically relevant; clinical relevance; Evidence based intervention; suicidal patient; suicide patient; user centered design; iterative design; trial comparing; functional improvement; function improvement; prototype; public health relevance; evidence base; reducing suicide; reduce suicidality; reduce suicide; reducing suicidality; flexibility; flexible; screening; Emergency Department patient; ED patient; ER patient; Emergency Room patient; formative assessment; formative evaluation; smartphone Application; Android App; Android Application; Cell Phone Application; Cell phone App; Cellular Phone App; Cellular Phone Application; Smart Phone App; Smart Phone Application; Smartphone App; iOS app; iOS application; iPhone App; iPhone Application; care providers; primary care provider; health goals; Home

Phase II

Contract Number: 4R44AA029868-02
Start Date: 9/1/2021    Completed: 8/31/2024
Phase II year
2022
(last award dollars: 2023)
Phase II Amount
$1,834,686

Suicide remains a serious public health problem in the U.S. as rates have risen nearly each year since 2005, from 11.0 per 100,000 to 14.8 per 100,000 in 2018, totaling 48,344 in 2018; 1.4 million U.S. adults made a suicide attempt, and another 12 million thought seriously about killing themselves that same year. Alcohol use disorder (AUD) exponentially increases suicide risk and can also interfere with suicide prevention intervention efforts. Suicide prevention initiatives over the past decade have targeted healthcare systems (HCS) in general and primary care clinics (PCC) in particular because so many who die by suicide access their primary care provider (PCP) in the months and year prior to their death. Though universal suicide screening is now routinely conducted in PCC, many HCS and PCC struggle to provide suicide prevention evidence-based practices (EBP) on par with other behavioral health EBP commonly treated in PCC. Digital technologies can efficiently and reliably help deliver suicide prevention EBP in PCC and increase the confidence and competence of PCP in treating suicide, including AUD that may interfere with these efforts. Jaspr Health ("Jaspr"; R44MH108222) is a suicide prevention platform originally designed for use by acutely suicidal patients in emergency departments (ED) to deliver suicide prevention EBP. Grounded in Jobes' Collaborative Assessment and Management of Suicidality (CAMS), Jaspr guides patients in completing a comprehensive suicide risk assessment and lethal means counseling, builds a crisis stabilization plan, and teaches behavioral skills to reduce imminent distress; videos of people with live experience (PLE) offer wisdom and hope for getting through suicide crises. Information is summarized for the care team to aid in discharge disposition planning. A companion app provides support post-discharge. Results from a randomized controlled trial (RCT; N=31) comparing Jaspr to Care-as-Usual strongly support its feasibility, acceptability, and effectiveness in increasing delivery of EBP, reducing agitation and distress, improving capacity to cope with suicidal thoughts, and improving ED satisfaction. This 34-month fast track seeks to increase the public health impact of Jaspr Health by extending its utility to deliver evidence-based brief interventions that directly target and treat a person's reasons for wanting to die (their "drivers" for suicide) while simultaneously addressing alcohol misuse. The proposal is defined by three project stages which include: (1) a proof-of-concept formative evaluation stage where we will iteratively design, test, and build a prototype (Phase I; Months 1-10); (2) a product design-and-build formative evaluation stage, where we will design, build and test all remaining features and apps (Phase II; Months 11- 22); and (3) a summative evaluation stage involving a pilot test (N=20) and a RCT (N=120) comparing Jaspr to a suicide prevention app and other online wellness resources (Phase II; Months 23-34).

Public Health Relevance Statement:


Project narrative:
PUBLIC HEALTH RELEVANCE With 47,151 suicides in 2019 and 12 million American adults reporting serious suicidal ideation each year, suicide remains the 10th leading cause of death among all ages and the second leading cause of death among those 10-44 years old in the U.S.; alcohol use disorder (AUD) exponentially increases suicide risk and can also interfere with suicide prevention intervention efforts. The Collaborative Assessment and Management for Suicidality (CAMS) is a flexible tool used to assess, manage, and treat suicidal behaviors. Jaspr Health ("Jaspr") is a robust CAMS-informed evidence-based digital technology that aids in assessing and managing acutely suicidal patients, this fast-track proposal seeks to extend its public health impact by developing brief interventions that directly target individuals' drivers of suicide in a primary care context.

Project Terms:
Adoption; Adult; 21+ years old; Adult Human; adulthood; Age; ages; alcohol use disorder; ethanol use disorder; Cause of Death; comorbidity; co-morbid; co-morbidity; Counseling; Cessation of life; Death; Health; Healthcare Systems; Health Care Systems; Health Personnel; Health Care Providers; Healthcare Providers; Healthcare worker; health care personnel; health care worker; health provider; health workforce; healthcare personnel; medical personnel; treatment provider; Mental Health Services; Mental Hygiene Services; mental health care; mental healthcare; Methods; Movement; body movement; Persons; Jobs; Professional Positions; Occupations; Out-patients; Outpatients; Painful; Pain; Patients; Primary Care; Primary Healthcare; Primary Health Care; Public Health; Research Resources; Resources; Running; fatal attempt; fatal suicide; intent to die; suicidality; Suicide; non fatal attempt; nonfatal attempt; suicidal attempt; Suicide attempt; Technology; Testing; Time; United States; Agitation; Psychomotor Agitation; Psychomotor Excitement; Psychomotor Hyperactivity; Psychomotor Restlessness; Restlessness; Administrator; Competence; Healthcare; health care; Research Methodology; Research Methods; Risk Assessment; Treatment Effectiveness; Caring; base; improved; Procedures; Suicide prevention; Suicide precaution; prevent suicidality; prevent suicide; suicidality prevention; suicide intervention; Acute; Phase; Ensure; Evaluation; Distress; Individual; Recovery; satisfaction; participant recruitment; Patient Recruitments; randomized control trial; Randomized Controlled Trials; Contracting Opportunities; Contracts; Companions; tool; Suicidal thoughts; suicidal ideation; suicidal thinking; suicide ideation; thoughts about suicide; Feeling suicidal; suicidal; Clinic; Visit; Emergency Department; Emergency room; Accident and Emergency department; suicide risk; suicidal risk; American; experience; Self Efficacy; skills; Participant; Preventative strategy; Preventive strategy; Prevention strategy; Manpower; personnel; Human Resources; Reporting; feeling distress; feeling upset; emotional distress; brief therapy; brief treatment; brief intervention; behavioral health; Effectiveness; Address; Evidence based practice; Preventative intervention; intervention for prevention; prevention intervention; preventional intervention strategy; preventive intervention; Process; Development; developmental; Behavioral; active control; suicidal behavior; suicide behavior; digital; design; designing; alcohol misuse; ethanol misuse; unhealthy alcohol use; coping; clinically relevant; clinical relevance; Evidence based intervention; suicidal patient; suicide patient; user centered design; iterative design; trial comparing; functional improvement; function improvement; prototype; public health relevance; evidence base; reducing suicide; reduce suicidality; reduce suicide; reducing suicidality; flexibility; flexible; screening; Emergency Department patient; ED patient; ER patient; Emergency Room patient; formative assessment; formative evaluation; smartphone Application; Android App; Android Application; Cell Phone Application; Cell phone App; Cellular Phone App; Cellular Phone Application; Smart Phone App; Smart Phone Application; Smartphone App; iOS app; iOS application; iPhone App; iPhone Application; care providers; primary care provider; health goals; Home; pilot test; design-build-test