SBIR-STTR Award

Prototype Multimedia ADRD Falls Prevention System for Family Caregivers
Award last edited on: 5/19/2023

Sponsored Program
SBIR
Awarding Agency
NIH : NIA
Total Award Amount
$274,754
Award Phase
1
Solicitation Topic Code
866
Principal Investigator
Victoria P Panzer

Company Information

Brookside Research & Development Company (AKA: Brookside R&D)

831 Pine Street
Edmonds, WA 98020
   (206) 317-3173
   vpbrookside@comcast.net
   N/A
Location: Single
Congr. District: 07
County: Snohomish

Phase I

Contract Number: 1R43AG071360-01A1
Start Date: 6/1/2021    Completed: 5/31/2022
Phase I year
2021
Phase I Amount
$246,663
Falls are a common and expensive problem, especially in persons with cognitive impairmentdue to Alzheimer's Disease and Related Dementias (PwADRD). Fall costs are expected to reach $67.7 billionthis year and add to family caregiver (CG) burden. Injurious falls are a frequent reason people are unable toremain at home, resulting in significantly increased care costs to the family and society. Most FP efforts fail to address understanding fall risks or changing behavior. In response to NIA requests for"˜Care technology to sustain in-home living, preserve function and promote effective communication', aninnovative falls prevention intervention for use by CGs of PwADRD living at home who are classified as atmoderate to high fall risk for falls will be developed and tested. Goal: Develop FallScape for Dementia (FS-D),an innovative CG-provided daily treatment utilizing proprietary multimedia and behavioral interventionmethods to facilitate communication and encourage FP behaviors that will reduce PwADRD falls. The rigorous Phase 1 research plan will: a) develop a FS-D prototype that includes CG trainingsoftware, multimedia and support tools to customize, conduct and review progress in daily CG-provided Mmsessions; b) Perform pilot testing and c) conduct a mixed methods preliminary clinical trial.Specific Aims and milestones/deliverables are: a) Develop prototype; i. Produce multimedia assets;ii. Craft Customization; iii. Artificial Intelligence algorithms; iv. Create CG training/daily administration tools.b) Pilot test prototype. i. Recruit 12 Dyads representing PwD diagnosed with Alzheimer's, vascular, Lewy-body and Parkinson's disease dementias. ii. Test CG ease of use and acceptability; iii. Examine customizationfor CG and dementia sub-types; iv. Evaluate relevance and dyad engagement.c) Conduct Preliminary Clinical Trial. 1. Recruit and enroll 25 Dyads; 2. Provide study components:initial; one-month FS-D intervention and a Follow-up; 3. Follow Dyads for 6 months; 4. Analyze outcomes anddisseminate results. FS-D will offer a rare opportunity to empower both CG and PwADRD by breaking the frustrating cycle offailure to recognize fall threats or change behavior and may mitigate CG burden. FS-D is an urgently neededfalls prevention intervention for family CG use. The economic and quality of life benefits of sustaining in-homeliving for PwADRD by preventing falls will accrue to all stakeholders for this large, high-risk population. Falls are a common and expensive problem, especially in persons with Alzheimer's disease and related Dementias (PwADRD) and the family caregiver (CG) is uniquely positioned to provide a positive daily interaction with the PwADRD in order to improve recognition of personal fall risks, encourage falls prevention behaviors and reduce falls. The proposed product FallScape- Dementia will develop and test a system for daily CG use in which Artificial Intelligence algorithms will guide the CG and customize the daily sessions. Reduction of falls will help the PwADRD to remain at home, reducing family and public health costs. Elderly ; advanced age ; elders ; geriatric ; late life ; later life ; older adult ; older person ; senior citizen ; Aging ; Algorithms ; Alzheimer's Disease ; AD dementia ; Alzheimer ; Alzheimer Type Dementia ; Alzheimer disease ; Alzheimer sclerosis ; Alzheimer syndrome ; Alzheimer's ; Alzheimer's disease dementia ; Alzheimers Dementia ; Alzheimers disease ; Primary Senile Degenerative Dementia ; dementia of the Alzheimer type ; primary degenerative dementia ; senile dementia of the Alzheimer type ; Artificial Intelligence ; AI system ; Computer Reasoning ; Machine Intelligence ; Award ; Behavior ; Behavior Therapy ; Behavior Conditioning Therapy ; Behavior Modification ; Behavior Treatment ; Behavioral Conditioning Therapy ; Behavioral Modification ; Behavioral Therapy ; Behavioral Treatment ; Conditioning Therapy ; behavior intervention ; behavioral intervention ; Blood Vessels ; vascular ; California ; Clinical Trials ; Communication ; Communities ; Diagnosis ; Economics ; Expenditure ; Family ; Foundations ; Future ; Gait ; Goals ; Hospitalization ; Hospital Admission ; Informed Consent ; Learning ; Long-Term Care ; extended care ; longterm care ; Los Angeles ; Methods ; Persons ; United States National Institutes of Health ; NIH ; National Institutes of Health ; Parkinson Disease ; Paralysis Agitans ; Parkinson ; Parkinson's disease ; Parkinsons disease ; Primary Parkinsonism ; Pilot Projects ; pilot study ; Public Health ; Quality of life ; QOL ; Psychological reinforcement ; Reinforcement ; Research ; research and development ; Development and Research ; R & D ; R&D ; Self Administration ; Self-Administered ; Societies ; Computer software ; Software ; Surveys ; Survey Instrument ; Technology ; Testing ; Washington ; Lewy Bodies ; Caregivers ; Care Givers ; Health Care Costs ; Health Costs ; Healthcare Costs ; falls ; Family Caregiver ; Family Care Giver ; Outcome Measure ; Fall prevention ; preventing falls ; Caring ; Custom ; Clip ; improved ; Phase ; Randomized Controlled Clinical Trials ; Evaluation ; Training ; Failure ; Databases ; Data Bases ; data base ; Collaborations ; tool ; Cognitive Disturbance ; Cognitive Impairment ; Cognitive decline ; Cognitive function abnormal ; Disturbance in cognition ; cognitive dysfunction ; cognitive loss ; Impaired cognition ; Multimedium ; Multimedia ; Protocol ; Protocols documentation ; System ; Amentia ; Dementia ; behavior change ; Visit ; meetings ; Family Health ; Family health status ; Structure ; novel ; member ; Devices ; Reporting ; Position ; Positioning Attribute ; Coding System ; Code ; Care giver Burden ; care giver stress ; caregiver stress ; Caregiver Burden ; response ; muscle strengthening ; resistance training ; strength training ; Intervention Strategies ; interventional strategy ; Intervention ; fall risk ; Address ; Symptoms ; Caregiver instruction ; care giver education ; care giver instruction ; care giver training ; caregiver training ; caregiver education ; Preventative intervention ; intervention for prevention ; prevention intervention ; preventional intervention strategy ; preventive intervention ; Enrollment ; enroll ; Characteristics ; follow-up ; Active Follow-up ; active followup ; follow up ; followed up ; followup ; cost ; Parkinson's Dementia ; PD with dementia ; Parkinson Dementia ; Parkinson Disease dementia ; Parkinson Disease with dementia ; Parkinson's Disease dementia ; Parkinson's disease with dementia ; dementia in PD ; dementia in Parkinson disease ; Outcome ; Balance training ; innovation ; innovate ; innovative ; prototype ; evidence base ; mild cognitive impairment ; mild cognitive disorder ; support tools ; formative assessment ; formative evaluation ; fall injury ; fall related injury ; injurious falls ; high risk population ; high risk group ; recruit ; care costs ; preservation ; Alzheimer's disease related dementia ; AD related dementia ; ADRD ; Alzheimer related dementia ; intelligent algorithm ; smart algorithm ; Alzheimer's disease diagnosis ; Alzheimer's diagnosis ; Home ;

Phase II

Contract Number: ----------
Start Date: 00/00/00    Completed: 00/00/00
Phase II year
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Phase II Amount
$28,091