
Rainbow Ultrafish: Rapid Sequential Rna Fish for Single-Cell Gene Expression AnalysisAward last edited on: 10/10/2019
Sponsored Program
SBIRAwarding Agency
NIH : NIGMSTotal Award Amount
$338,146Award Phase
1Solicitation Topic Code
-----Principal Investigator
Wei ZhangCompany Information
Phase I
Contract Number: ----------Start Date: ---- Completed: ----
Phase I year
2018Phase I Amount
$338,146Public Health Relevance Statement:
SBIR Project Narrative
Project narrative:
Rainbow UltraFISH is a technology that will enable researchers to analyze the expression patterns of hundreds to thousands of genes within single cells in the context of their normal tissue environment. With the coming of the spatial genomics era, UltraFISH will become an essential research tool for a very broad range of biologists and medical scientists in both academia and the biotech industry. It will help answer fundamental questions in all aspects of biology, as well as serve as a powerful tool to unravel the secrets of human disease.
Project Terms:
Academia; Adipose tissue; Architecture; base; Biological Assay; Biology; Biotechnology; Brain; Cell Line; Cells; Cellular biology; Collaborations; Color; Communities; Complex; Computer software; Cultured Cells; data acquisition; design; Detection; Development; Diagnostic; disease diagnosis; DNA; Environment; Fibrosis; Fluorescent in Situ Hybridization; Formaldehyde; Formalin; Freezing; Frozen Sections; Future; Gene Expression Profile; Gene Expression Profiling; Genes; Genomics; Hour; Human Cell Line; human disease; Image; Image Analysis; In Situ; Industry; instrument; Intellectual Property; interdisciplinary approach; Label; Laboratories; Liver; Medical; Methods; Molecular; Morphology; multidisciplinary; Mus; Normal tissue morphology; Oligonucleotide Probes; Oligonucleotides; osteosarcoma; Outcome; Paraffin Embedding; Pattern; personalized medicine; Phase; Population; precision medicine; Preparation; Process; Protocols documentation; Reagent; Research; Research Personnel; Resolution; Retrieval; RNA; RNA analysis; Running; sample fixation; Sampling; Scheme; Scientist; single cell technology; single molecule; single-cell RNA sequencing; Small Business Innovation Research Grant; Stem cells; Structure of parenchyma of lung; Structure of retinal pigment epithelium; System; Techniques; Technology; Testing; Time; Tissue Embedding; Tissue Sample; Tissues; tool; Work
Phase II
Contract Number: ----------Start Date: ---- Completed: ----