SBIR-STTR Award

Development of Fully Integrated Electrochemical Device for Detecting Metals in Biological Fluids
Award last edited on: 3/26/19

Sponsored Program
STTR
Awarding Agency
NIH : NIEHS
Total Award Amount
$149,999
Award Phase
1
Solicitation Topic Code
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Principal Investigator
James Hill

Company Information

Bioanalytical Systems Inc (AKA: BASi)

2701 Kent Avenue
West Lafayette, IN 47906
   (765) 463-4527
   N/A
   www.basinc.com

Research Institution

Frauhofer Center for Coatings

Phase I

Contract Number: 1R41ES029873-01
Start Date: 9/18/18    Completed: 8/31/19
Phase I year
2018
Phase I Amount
$149,999
Exposure to toxic levels of metals causes significant negative chronic health problems in the exposed populations. During and after exposure, metals such as manganese, lead, nickel, mercury, etc. are present in biological fluids. A fully integrated wearable device would enable real time monitoring of exposure levels. This would quickly alert those exposed to toxic concentrations of metals and mitigate the chronic health problems caused by exposure. Bioanalytical Systems Inc. will partner with Fraunhofer USA, Inc. Center for Coatings and Diamond Technologies to develop wearable device for the continuous monitoring of metals in biological fluids such as sweat. Fraunhofer USA, Inc. will optimize the geometry of flexible boron-doped diamond electrodes with multiple working electrode for use with a multiplexer potentiostat developed by Bioanalytical Systems Inc. This device will be capable of detecting metals at the concentration levels present in sweat through anodic and cathodic stripping voltammetry and the wearable device will be a battery powered potentiostat capable of Bluetooth communication and will be controlled by a cell phone or tablet.

Project Terms:
Achievement; Affect; Air; Android; Anodes; arm; base; Biological; biomaterial compatibility; Bluetooth; Boron; Businesses; Cadmium; Cathodes; Cellular Phone; Chemicals; Child; Chronic; collaborative environment; Communication; Communities; cost; density; design; Detection; Development; Devices; Diamond; Electrodes; Environment; Event; Exhibits; Exposure to; Film; flexibility; Future; Geometry; Health; Heavy Metals; improved; Individual; innovation; instrument; instrumentation; Ions; Lead; light weight; Liquid substance; Location; Manganese; Measurement; Measures; mechanical properties; Mechanics; member; Membrane; Mercury; Metal exposure; Metals; Methods; Microfabrication; Miniaturization; Mining; Monitor; multidisciplinary; Neurotransmitters; Nickel; parylene C; Pattern; Performance; Poisons; Polymers; Population; portability; Property; real time monitoring; Resistance; response; Saliva; sensor; Signal Transduction; smartphone Application; software development; Sports; Sweat; System; Tablets; Techniques; Technology; Technology Transfer; Thinness; tool; Urine; user friendly software; Water; wearable device; Work; Zinc;

Phase II

Contract Number: ----------
Start Date: 00/00/00    Completed: 00/00/00
Phase II year
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Phase II Amount
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