Patient-Specific Disposable Needle Guide: Alternative to In-Bore Robotics for Mri-Guided Transperineal Prostate Biopsy
Award last edited on: 1/10/2017

Sponsored Program
Awarding Agency
Total Award Amount
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Solicitation Topic Code

Principal Investigator
John C Magill

Company Information

Harmonus Inc

110 Canal Street Third Floor
Lowell, MA 01852
   (508) 208-1711
Location: Single
Congr. District: 03
County: Middlesex

Phase I

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Harmonus Inc. is proposing to develop a patient­specific disposable tool for directing needle entry during MRI­guided prostate biopy. Prostate cancer is the second leading cause of cancer death in the U.S. Over 225,000 cases of cancer were diagnosed in 2014 with almost 30,000 deaths. Prostate cancer is treatable, if properly diagnosed. By accurately targeting MRI­visible regions suspected of containing cancer, our system will improve the ability to find life­threatening tumors and reducethe chance of unnecessarily treating low­risk cases compared to current methods. Fabrication will be based on a rapid, precision machine for creating the guide from a sterile ki. In Phase I we will (I) Develop and demonstrate our novel method for producing the guides and (2) Verify that the manufacturing process maintains sterility of the guide. The product, after successful applications in biopsies, can be extended for use in other MRI­guided procedures and treatments for prostate cancer.

Public Health Relevance Statement:

Public Health Relevance:
Harmonus Inc. is proposing to develop a patient­specific needle guide for directing needle entry during MRI­guided prostate biopsy. The proposed research will benefit public health by improving patient quality of life through increased identification of aggressive cancer, reduced overtreatment of non­aggressive tumors and reduced biopsy complications associated with current prostate biopsy methods. Our approach will reduce infection risk and will be less expensive than robotic systems offered as alternatives

Project Terms:
Address; Antibiotics; Apical; Bacteria; base; Biopsy; cancer diagnosis; Cancer Etiology; Cessation of life; Clinical; cost; Custom; design; Devices; Diagnosis; Diagnostic; Dimensions; Discipline; Dose; drug resistant bacteria; Elasticity; Elements; Engineering; Ensure; experience; Fostering; Generations; Health; Hospitals; image guided; Image Guided Biopsy; Imaging Phantoms; imaging software; improved; Infection; Investments; Life; Location; Magnetic Resonance Imaging; Malignant neoplasm of prostate; Malignant Neoplasms; Manufacturer Name; manufacturing process; Medical Device; Medical Imaging; member; Methods; Nature; Needles; novel; Patients; Phase; Positioning Attribute; Procedures; Process; programs; prophylactic; Prostate; prostate biopsy; Public Health; Quality of life; rectal; Rectum; Research; research and development; Research Personnel; Resolution; Risk; Robot; robotic device; Robotics; Sampling; Scanning; skills; Small Business Innovation Research Grant; Sterility; success; System; Techniques; Technology; tool; Transrectal Ultrasound; tumor; Ultrasonography; Welding; Woman; Work

Phase II

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