SBIR-STTR Award

Advanced Image Analysis Tools for Diabetic Retinopathy Telemedicine Applications
Award last edited on: 2/12/2019

Sponsored Program
SBIR
Awarding Agency
NIH : NEI
Total Award Amount
$4,183,931
Award Phase
2
Solicitation Topic Code
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Principal Investigator
Kaushal Solanki

Company Information

Eyenuk Inc (AKA: Eyenuk LLC)

5850 Canoga Avenue Suite. 250
Woodland Hills, CA 91367
   (818) 835-3585
   info@eyenuk.com
   www.eyenuk.com
Location: Single
Congr. District: 32
County: Los Angeles

Phase I

Contract Number: 1R43EB013585-01A1
Start Date: 5/8/2012    Completed: 4/30/2014
Phase I year
2012
Phase I Amount
$199,915
In this small business innovations research (SBIR) project, we present aiArt: Advanced Image Analysis Tools for Diabetic Retinopathy Telemedicine applications. aiArt (pronounced eye-art), with its automated image analysis tools and user-friendly telemedicine web-interface, will enable exponential expansion of diabetic retinopathy screenings, thus fulfilling a significant health need as the number of people with diabetes climbs over the years. Latino population is genetically more prone to diabetes. Factors such as lack of awareness, lack of insurance coverage, and lack of access to expert clinicians greatly increase this disparity population's vulnerability to blindness due to DR. The situation is particularly grim in Los Angeles County, where there is a backlog of several thousand patients waiting to see an ophthalmologist, causing very long appointment wait times (often over six months). To help reduce risk of vision loss in this population, we propose to use advanced image analysis algorithms in conjunction with existing telemedicine initiatives to enable faster screening, allow reprioritization of ophthalmologist appointments, and to provide patient education tools. Our automated image analysis algorithms represent cutting-edge of research in image processing, computer vision, and machine learning. The analysis engine will be closely integrated with simple, easy-to-use web-based telemedicine infrastructure provided by an existing, popular, telemedicine initiative, EyePACS.

Public Health Relevance:
Narrative The proposed image analysis tools will greatly reduce the cost of diabetic retinopathy screening, and with its web and mobile phone accessible interface will drive an expansion of diabetic retinopathy screening, making it accessible to disparity populations (such as Latinos) which are not currently being screened due to socio-economic factors. The proposed tools will also enable quick turnaround time for screening, thus further helping prevent blindness due to diabetes complications.

Public Health Relevance Statement:
Narrative The proposed image analysis tools will greatly reduce the cost of diabetic retinopathy screening, and with its web and mobile phone accessible interface will drive an expansion of diabetic retinopathy screening, making it accessible to disparity populations (such as Latinos) which are not currently being screened due to socio-economic factors. The proposed tools will also enable quick turnaround time for screening, thus further helping prevent blindness due to diabetes complications.

NIH Spending Category:
Bioengineering; Clinical Research; Diabetes; Eye Disease and Disorders of Vision; Health Services; Networking and Information Technology R&D; Prevention; Rural Health

Project Terms:
abstracting; Address; Agreement; Algorithms; Appointment; Architecture; Area; Arts; Awareness; base; bioimaging; Blindness; California; Car Phone; Clinic; Clinical; Code; Complications of Diabetes Mellitus; Computer software; Computer Vision Systems; computerized data processing; Consult; cost; cotton wool spots; County; Detection; Diabetes Mellitus; diabetes risk; Diabetic Retinopathy; Dictionary; Disadvantaged; Economic Factors; Ensure; experience; Exudate; Eye; Faculty; Feedback; Goals; Gold; Health; Healthcare; Hemorrhage; Hispanics; Human; Image; Image Analysis; image processing; Incidence; Institutes; Insurance Coverage; Internet; Joints; Latino; Lesion; Localized Lesion; Location; Los Angeles; Machine Learning; Measures; Medical center; Microaneurysm; neovascularization; Online Systems; Ophthalmologist; Optometry; Patient Education; Patients; Phase; Plug-in; Population; Populations at Risk; prevent; Primary Health Care; Principal Investigator; Process; prototype; Reading; Reproducibility; Research; Research Infrastructure; Research Project Grants; Retinal Diseases; Risk; ROC Curve; Rural; Rural Health; Screening procedure; Sensitivity and Specificity; Severities; Side; Small Business Innovation Research Grant; socioeconomics; Software Design; Software Engineering; Software Tools; Statistical Computing; success; System; Telemedicine; Testing; Time; tool; tv watching; Universities; user-friendly; web interface; Work

Phase II

Contract Number: 5R43EB013585-02
Start Date: 5/8/2012    Completed: 9/30/2014
Phase II year
2013
(last award dollars: 2018)
Phase II Amount
$3,984,016

In this small business innovations research (SBIR) project, we present aiArt: Advanced Image Analysis Tools for Diabetic Retinopathy Telemedicine applications. aiArt (pronounced eye-art), with its automated image analysis tools and user-friendly telemedicine web-interface, will enable exponential expansion of diabetic retinopathy screenings, thus fulfilling a significant health need as the number of people with diabetes climbs over the years. Latino population is genetically more prone to diabetes. Factors such as lack of awareness, lack of insurance coverage, and lack of access to expert clinicians greatly increase this disparity population's vulnerability to blindness due to DR. The situation is particularly grim in Los Angeles County, where there is a backlog of several thousand patients waiting to see an ophthalmologist, causing very long appointment wait times (often over six months). To help reduce risk of vision loss in this population, we propose to use advanced image analysis algorithms in conjunction with existing telemedicine initiatives to enable faster screening, allow reprioritization of ophthalmologist appointments, and to provide patient education tools. Our automated image analysis algorithms represent cutting-edge of research in image processing, computer vision, and machine learning. The analysis engine will be closely integrated with simple, easy-to-use web-based telemedicine infrastructure provided by an existing, popular, telemedicine initiative, EyePACS.

Public Health Relevance Statement:


Public Health Relevance:
Narrative The proposed image analysis tools will greatly reduce the cost of diabetic retinopathy screening, and with its web and mobile phone accessible interface will drive an expansion of diabetic retinopathy screening, making it accessible to disparity populations (such as Latinos) which are not currently being screened due to socio-economic factors. The proposed tools will also enable quick turnaround time for screening, thus further helping prevent blindness due to diabetes complications.

NIH Spending Category:
Bioengineering; Clinical Research; Diabetes; Eye Disease and Disorders of Vision; Health Services; Networking and Information Technology R&D; Rural Health

Project Terms:
abstracting; Address; Agreement; Algorithms; Appointment; Architecture; Area; Arts; Awareness; base; bioimaging; Blindness; California; Car Phone; Clinic; Clinical; Code; Complications of Diabetes Mellitus; Computer software; Computer Vision Systems; computerized data processing; Consult; cost; cotton wool spots; County; Detection; Diabetes Mellitus; diabetes risk; Diabetic Retinopathy; Dictionary; Disadvantaged; Economic Factors; Ensure; experience; Exudate; Eye; Faculty; Feedback; Goals; Gold; Health; Healthcare; Hemorrhage; Hispanics; Human; Image; Image Analysis; image processing; Incidence; Institutes; Insurance Coverage; Internet; Joints; Latino; Lesion; Localized Lesion; Location; Los Angeles; Machine Learning; Measures; Medical center; Microaneurysm; neovascularization; Online Systems; Ophthalmologist; Optometry; Patient Education; Patients; Phase; Plug-in; Population; Populations at Risk; prevent; Primary Health Care; Principal Investigator; Process; prototype; public health relevance; Reading; Reproducibility; Research; Research Infrastructure; Research Project Grants; Retinal Diseases; Risk; ROC Curve; Rural; Rural Health; screening; Sensitivity and Specificity; Severities; Side; Small Business Innovation Research Grant; socioeconomics; Software Design; Software Engineering; Software Tools; Statistical Computing; success; System; Telemedicine; Testing; Time; tool; tv watching; Universities; user-friendly; web interface; Work