
High Resolution Maldi-Tof Mass SpectrometerAward last edited on: 12/29/11
Sponsored Program
SBIRAwarding Agency
NIH : NCRRTotal Award Amount
$1,183,005Award Phase
2Solicitation Topic Code
-----Principal Investigator
Marvin L VestalCompany Information
Virgin Instruments Corporation (AKA: Simultof Systems)
Location: Single
Congr. District: 05
County: Middlesex
Congr. District: 05
County: Middlesex
Phase I
Contract Number: 1R44RR025705-01Start Date: 3/1/09 Completed: 2/28/12
Phase I year
2009Phase I Amount
$100,000Public Health Relevance:
The proposed instrument is a vital component of new integrated analytical systems based on MALDI that will make large-scale proteomics and metabolomics practical. Completion of the human genome project and improved methods for analyzing proteins and small molecules in complex biological samples have been widely predicted to dramatically change drug discovery and clinical practice of medicine in the near future, but this has not yet been realized. Current technology is clearly not up to the task.
Public Health Relevance:
Relevance The proposed instrument is a vital component of new integrated analytical systems based on MALDI that will make large-scale proteomics and metabolomics practical. Completion of the human genome project and improved methods for analyzing proteins and small molecules in complex biological samples have been widely predicted to dramatically change drug discovery and clinical practice of medicine in the near future, but this has not yet been realized. Current technology is clearly not up to the task.
Thesaurus Terms:
There Are No Thesaurus Terms On File For This Project.
Phase II
Contract Number: 5R44RR025705-02Start Date: 3/1/09 Completed: 2/28/12
Phase II year
2010(last award dollars: 2011)
Phase II Amount
$1,083,005Public Health Relevance:
The proposed instrument is a vital component of new integrated analytical systems based on MALDI that will make large-scale proteomics and metabolomics practical. Completion of the human genome project and improved methods for analyzing proteins and small molecules in complex biological samples have been widely predicted to dramatically change drug discovery and clinical practice of medicine in the near future, but this has not yet been realized. Current technology is clearly not up to the task.
Thesaurus Terms:
Area; Biological; Calibration; Chromatography; Chromatography / Separation Science; Collaborations; Complex; Computer Programs; Computer Software; Detection; Drug Formulations; Esi; Electrospray Ionization; Elements; Engineering; Engineerings; Evaluation; Family; Formulation; Formulations, Drug; Fourier Transform Ion Cyclotron Resonance; Future; Gel; Goals; Human Genome Project; Instrumentation, Other; Intervention; Intervention Strategies; Mald-Ms; Maldi; Maldi-Ms; Maldi-Tof Mass Spectrometry; Maintenance; Maintenances; Marketing; Matrix-Assisted Laser Desorption Ionization Time-Of-Flight Ms; Matrix-Assisted Laser Desorption/Ionization Time-Of-Flight Mass Spectrometry; Measurement; Medicine; Methods; Operation; Operative Procedures; Operative Surgical Procedures; Peptides; Performance; Phase; Preparation; Price Lists; Price Lists [publication Type]; Procedures; Production; Protein Analysis; Proteins; Proteomics; Protocol; Protocols Documentation; Relative; Relative (Related Person); Reliability Of Results; Research Design; Resolution; Sampling; Science Of Medicine; Software; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectroscopy, Mass, Matrix-Assisted Laser Desorption-Ionization; Speed; Speed (Motion); Spottings; Study Type; Surgical; Surgical Interventions; Surgical Procedure; System; System, Loinc Axis 4; Technology; Time; Timeline; Work; Base; Clinical Practice; Commercialization; Computer Program/Software; Cost; Design; Designing; Develop Software; Developing Computer Software; Drug Discovery; Engineering Design; Fibrinopeptide; Gene Product; Improved; Instrument; Instrumentation; Interventional Strategy; Mass Spectrometer; Matrix Assisted Laser Desorption Ionization; Measurement Of Metabolism; Member; Metabolomics; Performance Tests; Price Lists; Prototype; Public Health Relevance; Small Molecule; Software Development; Study Design; Surgery; Tool