SBIR-STTR Award

Personal Ozone Monitor
Award last edited on: 7/3/12

Sponsored Program
SBIR
Awarding Agency
NIH : NIEHS
Total Award Amount
$834,852
Award Phase
2
Solicitation Topic Code
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Principal Investigator
John W Birks

Company Information

2B Technologies Inc (AKA: InDevR~2B Technology)

2100 Central Avenue Suite 105
Boulder, CO 80301
   (303) 273-0559
   sales@twobtech.com
   www.twobtech.com
Location: Single
Congr. District: 02
County: Boulder

Phase I

Contract Number: 1R43ES016925-01
Start Date: 00/00/00    Completed: 00/00/00
Phase I year
2008
Phase I Amount
$98,622
In this proposal we respond to the call by the National Institute of Environmental Health Sciences (NIEHS) in the PHS 2007-2 Omnibus Solicitation for "new products/devices, tools, assays to improve our ability to precisely measure environmental exposures to individuals with high temporal and spatial resolution." According to the solicitation, the device should be of appropriate scale to be field deployable and/or wearable. Ozone, formed in photochemical air pollution, has well documented adverse effects on human health, including reduction of lung function and aggravation of preexisting respiratory disease such as asthma. Emergency department visits, daily hospital admissions and mortality increase during episodes of high ozone concentration. A Personal Ozone Monitor (POM) is required for environmental health studies of the physiological effects of ozone and for validating computer models of human exposure such as the Air Pollution Exposure (APEX) model used by the Environmental Protection Agency to assist in establishing national air quality standards. We propose to develop a small (4 x 3 x 1 inch), light weight (d 1 lb), low power (d 3 watts), low cost (d $800 in parts) battery-operated POM based on the well established method of UV absorbance. The instrument will result from further miniaturization of a backpack-sized instrument already commercialized by 2B Technologies and successfully tested as a personal exposure monitor. The pocket-sized POM will have a precision and accuracy of better than 2 ppb and make new measurements every 10 s. The instrument will have an internal data logger and USB computer interface for downloading data into a personal computer. During Phase I, we will evaluate and select miniaturized components, design and construct a prototype POM, test the prototype for effects of orientation, vibration and rapid temperature and humidity change, and, finally, characterize the instrument with respect to the analytical figures of merit of linearity, precision and accuracy.

Public Health Relevance:
A pocket-sized, battery powered Personal Ozone Monitor (POM) will be developed and tested. The POM, which will be based on the well established method of UV absorbance, will facilitate physiological studies of the adverse effects of ozone, formed in air pollution, on human health.

Public Health Relevance:
This Public Health Relevance is not available.

Thesaurus Terms:
There Are No Thesaurus Terms On File For This Project.

Phase II

Contract Number: 2R44ES016925-02
Start Date: 9/1/08    Completed: 8/31/12
Phase II year
2010
(last award dollars: 2011)
Phase II Amount
$736,230

In this proposal we respond to the call by the National Institute of Environmental Health Sciences (NIEHS) in the PHS 2009-2 Omnibus Solicitation, Exposure Biology Program, Section 1, Technologies for Generating Precise Measures of Environmental Exposures for ""new products/devices, tools, assays to improve our ability to precisely measure environmental exposures to individuals with high temporal and spatial resolution."" According to the solicitation, the device should be of appropriate scale to be field deployable and/or wearable. Ozone, formed in photochemical air pollution, has well documented adverse effects on human health, including reduction of lung function and aggravation of preexisting respiratory disease such as asthma. Emergency department visits, daily hospital admissions and mortality increase during episodes of high ozone concentration. A Personal Ozone Monitor (POM) is required for environmental health studies of the physiological effects of ozone and for validating computer models of human exposure. In the Phase I project we successfully developed a small (4 x 3 x 1.5 inch), light weight (0.7 lb), low power (2.9 watts), low cost ($795 in parts), battery-operated POM based on the well established method of UV absorbance (an EPA Federal Reference Method). The pocket-sized POM has a precision and accuracy of # 2 ppb, makes new measurements every 10 s and has an internal data logger for downloading data to a personal computer. During the Phase II project proposed here, we will further improve and finalize the development of the POM to include the following: 1) dedicated ground plane on the printed circuit board to further reduce noise, 2) ruggedized, easily manufactured enclosure, 3) human interface consisting of liquid crystal display and keypad, 4) docking station with battery charger, 5) GPS for co-locating measurements with geographical coordinates, and 6) wireless communication between the POM and docking station. Firmware will be developed to support the new functions, and software will be developed for data acquisition and graphing by a computer and for uploading ozone data to the web. The efficacy and accuracy of the POM will be evaluated in personal exposure monitoring studies conducted at the Environmental and Occupational Health Sciences Institute (EOHSI) of the University of Medicine and Dentistry of New Jersey. Several large markets for a pocket-sized ozone monitor have been identified in addition to personal ozone monitoring;these include rapidly growing industrial applications of ozone and the Global Ozone (GO3) Project, an international educational project in which high school students build and operate an ozone monitoring station and share their data as an overlay on the Google Earth"" map. , ,

Public Health Relevance:
Development of a pocket-sized, battery powered Personal Ozone Monitor (POM) will be completed and evaluated as a means of measuring the time-resolved exposure of individuals during normal daily activities. The POM will facilitate physiological studies of the adverse effects of ozone, formed in air pollution, on human health.

Thesaurus Terms:
0-11 Years Old;21+ Years Old;Accident And Emergency Department;Admission;Admission Activity;Adult;Adverse Effects;Air;Air Pollution;Assay;Asthma;Bioassay;Biologic Assays;Biological Assay;Biology;Bronchial Asthma;Charge;Chemical Interference;Child;Child Youth;Children (0-21);Communication;Computer Programs;Computer Simulation;Computer Software;Computerized Models;Computers;Data;Data Banks;Data Bases;Data Collection;Data Display;Databank, Electronic;Databanks;Database, Electronic;Databases;Dentistry;Development;Devices;Dimensions;Docking;Electronics;Emergency Department;Emergency Room;Environmental Exposure;Environmental Factor;Environmental Health;Environmental Health Science;Environmental Risk Factor;Exposure To;Goals;Graph;Hosp;Health;Health Sciences;Hospitals;Human;Human Activities;Human, Adult;Human, Child;Human, General;Humidity;Individual;Institutes;International;Internet;Location;Lung Diseases;Man (Taxonomy);Man, Modern;Maps;Marketing;Mathematical Model Simulation;Mathematical Models And Simulations;Measurement;Measures;Medicine;Membrane;Memory;Methods;Modeling;Models, Computer;Monitor;Mortality;Mortality Vital Statistics;National Institute Of Environmental Health Sciences;New Jersey;Noise;Occupational Health;Ozone;Pattern;Personal Computers;Personal Power;Persons;Phase;Physiologic;Physiological;Printing;Procedures;Programs (Pt);Programs [publication Type];Pulmonary Diseases;Pulmonary Disorder;Research;Resolution;Respiratory Disease;Respiratory Disorder;Respiratory System Disease;Respiratory System Disorder;Respiratory Physiology;Science Of Medicine;Scientist;Series;Side;Simulation, Computer Based;Software;Staging;Students;System;System, Loinc Axis 4;Technology;Testing;Time;Travel;Treatment Side Effects;Universities;Visit;Www;Wireless Technology;Writing;Adult Human (21+);Base;Children;Clinical Data Repository;Clinical Data Warehouse;Computational Modeling;Computational Models;Computational Simulation;Computer Based Models;Computer Program/Software;Computerized Modeling;Computerized Simulation;Cost;Data Acquisition;Data Exchange;Data Repository;Design;Design And Construction;Designing;Environmental Risk;Experience;Exposed Human Population;High School;Human Exposure;Improved;In Silico;Laptop;Light (Weight);Liquid Crystal;Lung Disorder;Lung Function;Meetings;Membrane Structure;Ozone Exposure;Personal Diary;Personal Log;Personal Log/Diary;Programs;Prototype;Public Health Relevance;Relational Database;Respiratory Function;Side Effect;Therapy Adverse Effect;Tool;Toxicant;Treatment Adverse Effect;Virtual Simulation;Volunteer;Web;Wireless;World Wide Web;Youngster