SBIR-STTR Award

Controlled Heat-Aided Transdermal Drug Delivery:Fentanyl
Award last edited on: 4/2/02

Sponsored Program
STTR
Awarding Agency
NIH : NIGMS
Total Award Amount
$142,248
Award Phase
1
Solicitation Topic Code
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Principal Investigator
Jie Zhang

Company Information

Zars Inc (AKA: Zars Pharma Inc)

1142 West 2320 South
Salt Lake City, UT 84119
   (801) 350-0202
   info@zars.com
   www.zars.com

Research Institution

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Phase I

Contract Number: 1R41GM060886-01A1
Start Date: 00/00/00    Completed: 00/00/00
Phase I year
2001
Phase I Amount
$142,248
The investigators believe the fentanyl transdermal patch currently available has several limitations including the requirement of a long time to reach peak effect and that it cannot be used to treat breakthrough pain (short-lasting episodes of increased pain). ZARs' preliminary data, using its patented controlled, heat-aided drug delivery (CHADD) technology has demonstrated an ability to significantly enhance the dermal absorption of fentanyl from commercially available fentanyl skin patches. The aim of the proposed research is to develop a CHADD system that can significantly shorten the time it takes a fentanyl skin patch to reach peak effect and to prove the concept that CHADD can be utilized to produce a rapid bolus of fentanyl from skin patches, sufficient to treat breakthrough pain. PROPOSED COMMERCIAL APPLICATION: The commercial product will be prescribed by doctors for the treatment of both chronic pain (including severe cancer-related pain) and breakthrough pain (short-lasting episodes of increased pain).

Phase II

Contract Number: ----------
Start Date: 00/00/00    Completed: 00/00/00
Phase II year
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Phase II Amount
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