SBIR-STTR Award

Protein Scaffolds For Design Of Novel Anticancer Agents
Award last edited on: 6/16/08

Sponsored Program
SBIR
Awarding Agency
NIH : NCI
Total Award Amount
$1,403,397
Award Phase
2
Solicitation Topic Code
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Principal Investigator
Brent L Kreider

Company Information

Phylos Inc

128 Spring Street
Lexington, MA 02421
   (781) 862-6400
   N/A
   www.phylos.com
Location: Single
Congr. District: 05
County: Middlesex

Phase I

Contract Number: 1R43CA082956-01
Start Date: 00/00/00    Completed: 00/00/00
Phase I year
1999
Phase I Amount
$273,995
Phylos is developing in vitro RNA-protein fusion technology for the rapid identification, selection and engineering of proteins (including antibodies) with unique characteristics. As this technology does not require the use of classical antibodies Or their components, we will investigate the targeting Of small protein scaffolds that may be more suitable for pharmacological use. Further, as we are able to select rare proteins from very large libraries (>10(l4) members), we expect to select binders with a much higher affinity ie KD

Phase II

Contract Number: 5R43CA082956-02
Start Date: 00/00/00    Completed: 00/00/00
Phase II year
2000
(last award dollars: 2003)
Phase II Amount
$1,129,402

Phylos is developing in vitro RNA-protein fusion technology for the rapid identification, selection and engineering of proteins (including antibodies) with unique characteristics. As this technology does not require the use of classical antibodies Or their components, we will investigate the targeting Of small protein scaffolds that may be more suitable for pharmacological use. Further, as we are able to select rare proteins from very large libraries (>10(l4) members), we expect to select binders with a much higher affinity (i.e. KD