SBIR-STTR Award

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Microcoil-Based Probes For Capillary LC-NMR Detection
Award last edited on: 6/17/08

Sponsored Program
SBIR
Awarding Agency
NIH : NCRR
Total Award Amount
$1,205,187
Award Phase
2
Solicitation Topic Code
-----
Principal Investigator
Timothy Peck

Company Information

Magnetic Resonance Microsensors Corporation (AKA: MRM~Protesis)

101 Tomaras Avenue
Savoy, IL 61874
   (217) 351-4359
   N/A
   www.protasis.com/MRM/MRM_Home.htm
Location: Single
Congr. District: 13
County: Champaign

Phase I

Contract Number: 1R43RR014392-01
Start Date: 00/00/00    Completed: 00/00/00
Phase I year
1999
Phase I Amount
$116,717
The goal of this Fast-Track SBIR effort is to enable NMR detection for capillary LC (CapLC), by designing and rapidly commercializing a new family of microcoil-based NMR detection probes customized to interface with a CapLC system soon to be released by Waters Corporation (Milford, MA). This product brings together one of the best chromatography companies (Waters) with the Magnetic Resonance Microsensors (MRM) team responsible for development of the first ever picomole sensitivity probe for high resolution NMR. The primary benefit of this unique combination over existing products is enhanced NMR detection sensitivity and enhanced separation efficiency. The Specific Aims of Phase II quickly employ the results of the Phase I study to rapidly develop and deploy a Generation I CapLC-NMR probe to meet the immediate market opportunity provided by coincident release with the Waters CapLC. The Phase II effort then builds further upon the Phase I results to incorporate a series of product features designed to result in a probe that is performance-optimized and for capillary LC detection.

Thesaurus Terms:
contrast media, liquid chromatography, nuclear magnetic resonance spectroscopy, technology /technique development dye

Phase II

Contract Number: 2R44RR014392-02A1
Start Date: 00/00/00    Completed: 00/00/00
Phase II year
2001
(last award dollars: 2002)
Phase II Amount
$1,088,470
The goal of this Phase II SBIR effort is to enable for the first time a complete capillary-based NMR detection solution for capillary LC (cLC). The primary benefit of capillary LC is enhanced separation efficiency. The primary benefit of microcoil NMR probe technology is enhanced mass sensitivity while simultaneously maintaining superior fluidics and chromatographic integrity. SBIR funding will enable the MRM team responsible for development of the first ever picomole sensitivity probe for high resolution NMR to develop a series of probes performance-optimized for cLC. This hyphenated technology combination has high potential for significantly impacting the fields of drug discovery, chemical products development, and other analytical-based industries.

Thesaurus Terms:
liquid chromatography, nuclear magnetic resonance spectroscopy, reagent /indicator, technology /technique development dye