Bioadhesive Barrier For The Prevention Of Adhesions
Award last edited on: 3/3/02

Sponsored Program
Awarding Agency
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Principal Investigator
Herbert E Schwartz

Company Information

FzioMed Inc

231 Bonetti Drive
San Luis Obispo, CA 93401
   (805) 546-0610
Location: Single
Congr. District: 24
County: San Luis Obispo

Phase I

Contract Number: 1R43AR45350-01
Start Date: 00/00/00    Completed: 00/00/00
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(Adapted from applicant's abstract): Adhesive disease is a significant problem in current medical practice. Implantable biomaterials, serving as barriers between healing serosal surfaces and fibrin clots, are considered a viable solution to the problem. Following a research plan incorporating physicochemical and mechanical tests, as well as analytical separation techniques, MedDev Corporation will develop optimized bioadhesive barrier materials. The viscous fluid/gel or membrane materials are blends of carboxymethylcellulose and polyethylene oxide, internally stabilized through hydrogen bonding. Bioadhesiveness will be studied in an in-vitro tissue coating model. Optimized materials will be tested in two standard animal models for adhesions and scar formation in spinal and abdominal surgery.

Thesaurus Terms:
adhesion, biomaterial development /preparation, gel, methylcellulose, oxide, polymer biomaterial compatibility, biomaterial interface phenomena, implant, scarNational Institute of Arthritis and Musculosketal and Skin Diseases (NIAMS)

Phase II

Contract Number: ----------
Start Date: 00/00/00    Completed: 00/00/00
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