Daily use of a sonic toothbrush has been shown to significantly reduce supragingival plaque, subgingival bacteria, and periodontal pocket depth by combining mechanical scrubbing with cleaning beyond the bristles due to the dynamic fluid activity surrounding the brush head. The primary objective of the current application is to further enhance the efficacy of the sonic toothbrush. Laboratory evaluation of important brushing parameters will be conducted to assist in toothbrush enhancement. In vivo analysis of brushing patterns will compliment in vitro studies and lead to the accurate establishment of important brushing characteristics. This approach to enhancing toothbrush efficacy may provide high potential for improved oral health for both the general population and those with periodontal disease.National Institute of Dental Research (NIDR)