The development of Mechanical Circulatory Support Systems has been funded for more than 25 years by the NHLBI. These devices will be powered by electricity, in part, because electric power can be transmitted through intact skin using a transcutaneous energy transmission system, or TETS. As the animal experiments have progressed, there have arisen increasingly severe problems with adverse tissue response in the skin covering the subcutaneous TETS coil. An experiment is proposed to test the hypothesis that the tissue necrosis is caused by a combination of compromised skin perfusion and local heating associated with the TETS coils. An alternate coil configuration will be evaluated in animal experiments. During these evaluations, a well per fused muscle will be interposed between the TETS coils providing a convective transport mechanism, so heat can be carried away from the site. The experiments are to be carried out at one of the laboratories which has observed the problem with a conventional coil configuration. We have developed a TETS which has demonstrated excellent power transmission efficiency with the anticipated intercoil spacing. We will develop a commercial TETS which offers improved tissue viability.Awardee's statement of the potential commercial applications of the research: Newly developed circulatory support systems are beginning to enter clinical trials and are powered by a transcutaneous energy transmission system, or TETS. This research addresses a serious problem which has arisen in the course of recent experiments. Development of a successful TETS for artificial heart application has been projected to result in domestic annual sales of 35,000 to 70,000 units with an estimated value of several thousand dollars per unit.National Heart, Lung and Blood Institute (NHLBI)
