SBIR-STTR Award

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Monoclonal antibodies against the MHC of inbred rats
Award last edited on: 12/22/2014

Sponsored Program
SBIR
Awarding Agency
NIH : NCRR
Total Award Amount
$50,000
Award Phase
1
Solicitation Topic Code
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Principal Investigator
Harold Hoffman

Company Information

Animal Genetic Systems Inc

11 Taft Court
Rockville, MD 20850
   (301) 251-1101
   N/A
   N/A
Location: Single
Congr. District: 08
County: Montgomery

Phase I

Contract Number: 1R43RR003542-01
Start Date: 00/00/00    Completed: 00/00/00
Phase I year
1987
Phase I Amount
$50,000
The objectives of this proposal are to: (1) produce allotypic monoclonal antibodies that distinguish class I and class II antigens coded by the RTI loci major histocompatibility complex (MHC) in the laboratory rat, and (2) characterize the anti-MHC monoclonal antibodies by biochemical and genetic methods to determine their antigenic specificity for class I and class II antigens of different MHC haplotypes using strains of inbred rats. The antibodies will be used in combination with other procedures for genetic definition within the MHC.Phase I research included induction and chaYacterization of allotypic monoclonal antibodies against the 10 known haplotypes of the rat MHC. Phase II will include production and characterization of monoclonal antibodies against the 10 known haplotypes of the rat MHC.Division of Research Resources (NCRR)

Phase II

Contract Number: ----------
Start Date: 00/00/00    Completed: 00/00/00
Phase II year
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Phase II Amount
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