The development of a software package for the statistical analysis of epidemiological data and a package for the production of manuscript bibliographies is proposed. The user-friendly packages will be developed for implementation on IBM XT and AT systems for use by NCI research personnel. Phase I of this development effort will include the specification and design of the packages as well as the implementation and testing of prototype versions.The statistical analysis methods in the first package will include those specifically required by the special characteristics of epidemiological data. This package will include extensive online help for all aspects of its execution, data editing, and report writing capabilities, as well as data exploration and basic statistical analysis routines. Input and output of this package will be capable of easily interfacing with other programs used by NCI personnel for communication with mainframe computers and for additional data treatment.The bibliography production software will be capable of automatically reformatting a list of references according to the specifications of the journal in which a manuscript is intended for publication. The target journals included will be those used by NCI investigators for publication of their research.National Cancer Institute (NCI)