Phase II year
1986
(last award dollars: 1987)
A multimonitor endotracheal tube with sensors for ECG, temperature, heart sounds, and breath sounds was developed in Phase I studies and feasibility clearly demonstrated in dog experiments. ECG signals, heart and breath sounds, and temperature measured from a single anatomic site-the trachea-compared favorably with conventional monitors-surface ECG leads, esophageal stethoscope, and esophageal temperature. A Doppler attached to the endotracheal tube provided beat-to-beat heart and vascular sounds and sensitive detection of blood turbulence and/or minute quantities of vascular air.Phase II studies will refine these sensors, evaluate additional sensors on the endotracheal tube and perform toxicity studies on trachealsensor interface sites and complete durability testing. In conjunction with a large U.S. tracheal tube manufacturer, a family of multirnonitor endotracheal tubes will be fabricated and tested for human clinical trials. A disposable, cost-efficient, sensitive multimonitor endotracheal tube will replace many of the current individual vital signs monitoring devices.
Thesaurus Terms: Biomedical Engineering, Instrumentation Clinically Oriented, Biomedical Systems Automated, Patient Monitoring (Monitoring Devices), Cardiovascular Disorders Diagnosis, Blood Flow Measurements, Ultrasonic, Heart Disorders Diagnosis, Electrocardiography Monitor, Heart Disorders Diagnosis, Heart Sound Measurements, Respiratory Disorders Diagnosis, Respiratory Airflow Measurements, Respiratory System, Trachea, Temperature Measurement Health Care Services, Patient Care, Critical Care, Health Care Services, Patient Care, Emergency Care Mammals, Carnivores, Dogs National Heart, Lung, and Blood Institute (NHLBI)