SBIR-STTR Award

Hydrocarbon free extraction using supercritical fluids
Award last edited on: 4/19/02

Sponsored Program
SBIR
Awarding Agency
NIH : NIGMS
Total Award Amount
$550,000
Award Phase
2
Solicitation Topic Code
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Principal Investigator
Raymond K Houck

Company Information

Suprex Corporation

125 William Pitt Way
Pittsburgh, PA 15238
   (412) 826-5200
   N/A
   N/A
Location: Single
Congr. District: 17
County: Allegheny

Phase I

Contract Number: 1R43GM033692-01
Start Date: 00/00/00    Completed: 00/00/00
Phase I year
1984
Phase I Amount
$50,000
Technical feasibility research is being performed on the use of supercritical fluid to separate naturally occurring coloring and flavoring pigments from their botanical sources. Supercritical fluid technology is an innovation that substitutes compressed gases, at pressures and temperatures above their thermodynamic critical points, for liquid phase solvents. In this physical state, compressed gases have the solvating power of common liquid solvents, but retain the mass transfer and diffusion properties of a gas. Supercritical fluids are superior solvents for analyzing and purifying a wide range of organic and biological products.Currently used synthetic food colorants, such as FD&C Red No. 40, are suspected carcinogens. Natural red colorants are a potential alternative; however, current technology for the isolation of these colorants involves extraction with harmful organic solvents such as hexane, methanol, methylene chloride, and acetone. The application of supercritical fluid extraction for this purpose could provide an alternative supply of pure, solvent-free, noncarcinogenic natural coloring and flavoring compounds for food products.Anthocyanin-containing botanicals will be tested to determine the extractability of their pigment components with supercritical carbon dioxide. The effect of a number of experimental parameters on extraction rate will be studied and extracted pigments will be tested for color value and composition.National Institute Of General Medical Sciences

Phase II

Contract Number: 2R44GM033692-02
Start Date: 00/00/00    Completed: 00/00/00
Phase II year
1986
(last award dollars: 1987)
Phase II Amount
$500,000

Suprex Corporation will perform technical feasibility research on the use of supercritical fluids to separate naturally occurring coloring and flavoring pigments from their botanical sources. Supercritical fluids technology is an innovation that substitutes compressed gases, at pressures and temperatures above their thermodynamic critical points, for liquid phase solvents. In this physical state, compressed gases have the solvating power of common liquid solvents but retain the mass transfer and diffusion properties of a gas. Supercritical fluids are superior solvents for analyzing and purifying a wide range of organic and biological products.Currently used synthetic food colorants, such as FD&C Red No. 40, are suspected carcinogens.Natural red colorants are a potential alternative; however, current technology for the isolation of these colorants involves extraction with harmful organic solvents such as hexane, methanol, methylene chloride, and acetone. The application of supercritical fluid extraction for this purpose could provide an alternative supply of pure, solvent-free, noncarcinogenic natural coloring and flavoring compounds for food products.Suprex will test anthocyanin-containing botanicals to determine the extractability of their pigment components with supercritical carbon dioxide. The effect of number of experimental parameters on extraction rate will be studied, and extracted pigments will be tested for color value and composition.National Institute of General Medical Sciences